Literature DB >> 7056754

14 alpha-Ethyl-5 alpha-cholest-7-ene-3 beta,15 alpha-diol, a potent inhibitor of sterol biosynthesis, has two sites of action in cultured mammalian cells.

F D Pinkerton, A Izumi, C M Anderson, L R Miller, A Kisic, G J Schroepfer.   

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Year:  1982        PMID： 7056754

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  2 in total

1.  5 alpha-Cholest-8(14)-en-3 beta-ol-15-one, a potent inhibitor of sterol biosynthesis, lowers serum cholesterol and alters distributions of cholesterol in lipoproteins in baboons.

Authors:  G J Schroepfer; E J Parish; A Kisic; E M Jackson; C M Farley; G E Mott
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

2.  5 alpha-Cholest-8(14)-en-3 beta-ol-15-one lowers serum cholesterol and induces profound changes in the levels of lipoprotein cholesterol and apoproteins in monkeys fed a diet of moderate cholesterol content.

Authors:  G J Schroepfer; B C Sherrill; K S Wang; W K Wilson; A Kisic; T B Clarkson
Journal:  Proc Natl Acad Sci U S A       Date:  1984-11       Impact factor: 11.205
  2 in total

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