Literature DB >> 7045698

Synthesis and assembly of hepatitis B virus surface antigen particles in yeast.

P Valenzuela, A Medina, W J Rutter, G Ammerer, B D Hall.   

Abstract

The surface antigens of hepatitis B virus (HBsAg) has been synthesized in the yeast Saccharomyces cerevisiae by using an expression vector that employs the 5'-flanking region of yeast alcohol dehydrogenase I as a promotor to transcribe surface antigen coding sequences. The protein synthesized in yeast is assembled into particles having properties similar to the 22-nm particles secreted by human cells.

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Year:  1982        PMID： 7045698     DOI： 10.1038/298347a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  168 in total

Review 1.  Recent advances in vaccine adjuvants.

Authors:  Manmohan Singh; Derek T O'Hagan
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2.  Expression of hepatitis B surface antigen in transgenic plants.

Authors:  H S Mason; D M Lam; C J Arntzen
Journal:  Proc Natl Acad Sci U S A       Date:  1992-12-15       Impact factor: 11.205

3.  DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines.

Authors:  H L Davis; M J McCluskie; J L Gerin; R H Purcell
Journal:  Proc Natl Acad Sci U S A       Date:  1996-07-09       Impact factor: 11.205

4.  Studies in the development of Japanese encephalitis vaccine: expression of virus envelope glycoprotein V3 (E) gene in yeast.

Authors:  H Fujita; H Sumiyoshi; C Mori; S Manabe; M Takagi; I Yoshida; K Morita; I Fuke; K Fukai; A Igarashi
Journal:  Bull World Health Organ       Date:  1987       Impact factor: 9.408

Review 5.  Metabolic engineering of Saccharomyces cerevisiae.

Authors:  S Ostergaard; L Olsson; J Nielsen
Journal:  Microbiol Mol Biol Rev       Date:  2000-03       Impact factor: 11.056

6.  Expression of hepatitis B surface antigen in transgenic banana plants.

Authors:  G B Sunil Kumar; T R Ganapathi; C J Revathi; L Srinivas; V A Bapat
Journal:  Planta       Date:  2005-05-26       Impact factor: 4.116

Review 7.  Nature and display of hepatitis B virus envelope proteins and the humoral immune response.

Authors:  A Alberti; W H Gerlich; K H Heermann; P Pontisso
Journal:  Springer Semin Immunopathol       Date:  1990

8.  Domains of the Hepatitis B Virus Small Surface Protein S Mediating Oligomerization.

Authors:  Sascha Suffner; Nadine Gerstenberg; Maria Patra; Paula Ruibal; Ahmed Orabi; Michael Schindler; Volker Bruss
Journal:  J Virol       Date:  2018-05-14       Impact factor: 5.103

Review 9.  Revisiting Hepatitis B Virus: Challenges of Curative Therapies.

Authors:  Jianming Hu; Ulrike Protzer; Aleem Siddiqui
Journal:  J Virol       Date:  2019-09-30       Impact factor: 5.103

Review 10.  Hepatitis B virus infection. Current concepts of chronicity and immunity.

Authors:  G N Vyas; H E Blum
Journal:  West J Med       Date:  1984-05
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