| Literature DB >> 7040548 |
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Abstract
Theoretical and practical aspects of limiting dilution assays are considered, and the maximum likelihood solution is illustrated by two worked examples. These examples show up the inferiority of the conventional regression analysis, while the advantages of the maximum likelihood over minimum chi-square methods are covered in the discussion. A program, which will perform all the necessary calculations on a pocket calculator, is listed in the Appendix.Mesh:
Year: 1982 PMID: 7040548 DOI: 10.1016/0022-1759(82)90269-1
Source DB: PubMed Journal: J Immunol Methods ISSN: 0022-1759 Impact factor: 2.303