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Literature DB >> 7039768

A monoclonal antibody which binds to the surface of chick brain cells and myotubes: cell selectivity and properties of the antigen.

V Lemmon, E B Staros, H E Perry, D I Gottlieb.

Abstract

A monoclonal antibody has been obtained which binds to the cell surface of cultured chick myotubes and retinal and tectal neurons but not fibroblasts, myoblasts and embryonic liver cells. Indirect immunocytochemistry reveals that antigen is present in all layers of the chick neural retina. The antibody therefore recognizes an antigen common to most, if not all, chick neurons. The antigen has been identified by staining SDS gels with [125I]monoclonal antibody and appears to be a polydisperse collection of polypeptides with molecular weights centered about 250 kdalton.

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Year: 1982 PMID： 7039768 DOI： 10.1016/0165-3806(82)90003-7

Source DB: PubMed Journal: Brain Res ISSN： 0006-8993 Impact factor: 3.252

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Cited

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9. Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

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10. Topography of N-CAM structural and functional determinants. I. Classification of monoclonal antibody epitopes.

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A monoclonal antibody which binds to the surface of chick brain cells and myotubes: cell selectivity and properties of the antigen.

1. The Life of a Trailing Spouse.

2. An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension.

3. N-cadherin, NCAM, and integrins promote retinal neurite outgrowth on astrocytes in vitro.

4. Spatial and temporal expression of the 5A11/HT7 antigen in the chick embryo : Association with morphogenetic events and tissue maturation.

5. Neural cell adhesion molecule (N-CAM) accumulates in denervated and paralyzed skeletal muscles.

6. N-Cadherin and integrins: two receptor systems that mediate neuronal process outgrowth on astrocyte surfaces.

Review 7. Molecular mechanisms of cell adhesion in normal and transformed cells.

8. Identification of the major proteins that promote neuronal process outgrowth on Schwann cells in vitro.

9. Immunocytological and biochemical characterization of a new neuronal cell surface component (L1 antigen) which is involved in cell adhesion.

10. Topography of N-CAM structural and functional determinants. I. Classification of monoclonal antibody epitopes.