Literature DB >> 33408132

The Life of a Trailing Spouse.

Vance P Lemmon1.   

Abstract

In 1981, I published a paper in the first issue of the Journal of Neuroscience with my postdoctoral mentor, Alan Pearlman. It reported a quantitative analysis of the receptive field properties of neurons in reeler mouse visual cortex and the surprising conclusion that although the neuronal somas were strikingly malpositioned, their receptive fields were unchanged. This suggested that in mouse cortex at least, neuronal circuits have very robust systems in place to ensure the proper formation of connections. This had the unintended consequence of transforming me from an electrophysiologist into a cellular and molecular neuroscientist who studied cell adhesion molecules and the molecular mechanisms they use to regulate axon growth. It took me a surprisingly long time to appreciate that your science is driven by the people around you and by the technologies that are locally available. As a professional puzzler, I like all different kinds of puzzles, but the most fun puzzles involve playing with other puzzlers. This is my story of learning how to find like-minded puzzlers to solve riddles about axon growth and regeneration.
Copyright © 2021 the authors.

Entities:  

Mesh:

Year:  2021        PMID: 33408132      PMCID: PMC7786219          DOI: 10.1523/JNEUROSCI.2874-20.2020

Source DB:  PubMed          Journal:  J Neurosci        ISSN: 0270-6474            Impact factor:   6.167


  64 in total

1.  Challenges in small screening laboratories: implementing an on-demand laboratory information management system.

Authors:  Vance P Lemmon; Yuanyuan Jia; Yan Shi; S Douglas Holbrook; John L Bixby; William Buchser
Journal:  Comb Chem High Throughput Screen       Date:  2011-11       Impact factor: 1.339

2.  The mTOR Substrate S6 Kinase 1 (S6K1) Is a Negative Regulator of Axon Regeneration and a Potential Drug Target for Central Nervous System Injury.

Authors:  Hassan Al-Ali; Ying Ding; Tatiana Slepak; Wei Wu; Yan Sun; Yania Martinez; Xiao-Ming Xu; Vance P Lemmon; John L Bixby
Journal:  J Neurosci       Date:  2017-06-16       Impact factor: 6.167

3.  An L1-like molecule, the 8D9 antigen, is a potent substrate for neurite extension.

Authors:  C Lagenaur; V Lemmon
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

4.  The microtubule cytoskeleton and the development of neuronal polarity.

Authors:  J W Mandell; G A Banker
Journal:  Neurobiol Aging       Date:  1995 May-Jun       Impact factor: 4.673

5.  A monoclonal antibody which binds to the surface of chick brain cells and myotubes: cell selectivity and properties of the antigen.

Authors:  V Lemmon; E B Staros; H E Perry; D I Gottlieb
Journal:  Brain Res       Date:  1982-03       Impact factor: 3.252

6.  Activation of the MAPK signal cascade by the neural cell adhesion molecule L1 requires L1 internalization.

Authors:  A W Schaefer; H Kamiguchi; E V Wong; C M Beach; G Landreth; V Lemmon
Journal:  J Biol Chem       Date:  1999-12-31       Impact factor: 5.157

7.  Role of the cytoplasmic domain of the L1 cell adhesion molecule in brain development.

Authors:  Yukiko Nakamura; Suni Lee; Candace L Haddox; Eli J Weaver; Vance P Lemmon
Journal:  J Comp Neurol       Date:  2010-04-01       Impact factor: 3.215

8.  The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway.

Authors:  H Kamiguchi; K E Long; M Pendergast; A W Schaefer; I Rapoport; T Kirchhausen; V Lemmon
Journal:  J Neurosci       Date:  1998-07-15       Impact factor: 6.167

9.  PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure.

Authors:  Arnau Hervera; Luming Zhou; Ilaria Palmisano; Eilidh McLachlan; Guiping Kong; Thomas H Hutson; Matt C Danzi; Vance P Lemmon; John L Bixby; Andreu Matamoros-Angles; Kirsi Forsberg; Francesco De Virgiliis; Dina P Matheos; Janine Kwapis; Marcelo A Wood; Radhika Puttagunta; José Antonio Del Río; Simone Di Giovanni
Journal:  EMBO J       Date:  2019-05-22       Impact factor: 11.598

10.  EST Express: PHP/MySQL based automated annotation of ESTs from expression libraries.

Authors:  Robin P Smith; William J Buchser; Marcus B Lemmon; Jose R Pardinas; John L Bixby; Vance P Lemmon
Journal:  BMC Bioinformatics       Date:  2008-04-10       Impact factor: 3.169

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