Literature DB >> 7039617

The effect of limited proteolysis on rabbit muscle creatine kinase.

N C Price, S Murray, E J Milner-White.   

Abstract

Creatine kinase from rabbit muscle is inactivated by limited proteolysis with proteinase K from Tritirachium album. Gel-filtration and cross-linking studies showed that the limited proteolysis did not affect the molecular weight of the enzyme under non-denaturing conditions, but did cause changes in the reactivity of the reactive thiol group on each subunit and in the ability of the enzyme to form a 'transition-state analogue' complex in the presence of magnesium acetate plus ADP plus creatinine plus NaNO3.

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Year:  1981        PMID： 7039617      PMCID： PMC1163356          DOI： 10.1042/bj1990239

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  23 in total

1.  Preparation and properties of S-cyano derivatives of creatine kinase.

Authors:  E der Terrossian; R Kassab
Journal:  Eur J Biochem       Date:  1976-11-15

2.  Simple alkanethiol groups for temporary blocking of sulfhydryl groups of enzymes.

Authors:  D J Smith; E T Maggio; G L Kenyon
Journal:  Biochemistry       Date:  1975-02-25       Impact factor: 3.162

3.  Structure and function of aspartate transcarbamoylase studied using chymotrypsin as a probe.

Authors:  W W Chan; C A Enns
Journal:  Can J Biochem       Date:  1978-06

4.  Inhibition of adenosine 5'-triphosphate-creatine phosphotransferase by substrate-anion complexes. Evidence for the transition-state organization of the catalytic site.

Authors:  E J Milner-White; D C Watts
Journal:  Biochem J       Date:  1971-05       Impact factor: 3.857

5.  The refolding of denatured rabbit muscle creatine kinase.

Authors:  G F Bickerstaff; C Paterson; N C Price
Journal:  Biochim Biophys Acta       Date:  1980-02-27

6.  A study of the role of the reactive thiol group of rabbit muscle creatine kinase with a chromophoric reporter group.

Authors:  M A Keighren; N C Price
Journal:  Biochem J       Date:  1978-04-01       Impact factor: 3.857

7.  Use of pH studies to elucidate the catalytic mechanism of rabbit muscle creatine kinase.

Authors:  P F Cook; G L Kenyon; W W Cleland
Journal:  Biochemistry       Date:  1981-03-03       Impact factor: 3.162

8.  The reaction of rabbit muscle creatine kinase with diethyl pyrocarbonate.

Authors:  D E Clarke; N C Price
Journal:  Biochem J       Date:  1979-08-01       Impact factor: 3.857

9.  Properties of a CH3-blocked creatine kinase with altered catalytic activity. Kinetic consequences of the presence of the blocking group.

Authors:  E T Maggio; G L Kenyon
Journal:  J Biol Chem       Date:  1977-02-25       Impact factor: 5.157

10.  Heterogeneity of rabbit muscle creatine kinase and limited proteolysis by proteinase K.

Authors:  J Williamson; J Greene; S Chérif; E J Milner-White
Journal:  Biochem J       Date:  1977-12-01       Impact factor: 3.857
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  4 in total

1.  Hydrogen/deuterium exchange studies of native rabbit MM-CK dynamics.

Authors:  Hortense Mazon; Olivier Marcillat; Eric Forest; Christian Vial
Journal:  Protein Sci       Date:  2004-02       Impact factor: 6.725

2.  Specific proteolytic modification of creatine kinase isoenzymes. Implication of C-terminal involvement in enzymic activity but not in subunit-subunit recognition.

Authors:  H G Lebherz; T Burke; J E Shackelford; J E Strickler; K J Wilson
Journal:  Biochem J       Date:  1986-01-01       Impact factor: 3.857

3.  Monoclonal-antibody studies of creatine kinase. The proteinase K-cleavage site.

Authors:  G E Morris; L C Frost; L P Head
Journal:  Biochem J       Date:  1985-06-01       Impact factor: 3.857

4.  The refolding of denatured rabbit muscle creatine kinase. Search for intermediates in the refolding process and effect of modification at the reactive thiol group on refolding.

Authors:  N C Price; E Stevens
Journal:  Biochem J       Date:  1982-01-01       Impact factor: 3.857
  4 in total

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