Literature DB >> 7037740

Repression of cytosine deaminase by pyrimidines in Salmonella typhimurium.

T P West, G A O'Donovan.   

Abstract

The synthesis of cytosine deaminase in Salmonella typhimurium is repressed by pyrimidines. This repression is mediated by both a uridine and a cytidine compound, indicating a distinct difference in the regulation of synthesis of cytosine deaminase from the regulation of the de novo pyrimidine pathway enzymes. A salvage role for the enzyme in pyrimidine metabolism is postulated.

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Year:  1982        PMID： 7037740      PMCID： PMC216515          DOI： 10.1128/jb.149.3.1171-1174.1982

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  18 in total

1.  Control of expression of the pyr genes in Salmonella typhimurium: effects of variations in uridine and cytidine nucleotide pools.

Authors:  M Schwartz; J Neuhard
Journal:  J Bacteriol       Date:  1975-03       Impact factor: 3.490

2.  Nucleoside-catabolizing enzymes in Salmonella typhimurium. Introduction by ribonucleosides.

Authors:  P Nygaard
Journal:  Eur J Biochem       Date:  1973-07-02

3.  Mutants constitutive for nucleoside-catabolizing enzymes in Escherichia coli K12. Isolation, charactrization and mapping.

Authors:  A Munch-Petersen; P Nygaard; K Hammer-Jespersen; N Fiil
Journal:  Eur J Biochem       Date:  1972-05-23

4.  Metabolism of pyrimidines and pyrimidine nucleosides by Salmonella typhimurium.

Authors:  C F Beck; J L Ingraham; J Neuhard; E Thomassen
Journal:  J Bacteriol       Date:  1972-04       Impact factor: 3.490

Review 5.  Pyrimidine metabolism in microorganisms.

Authors:  G A O'Donovan; J Neuhard
Journal:  Bacteriol Rev       Date:  1970-09

6.  Mutants of Salmonella typhimurium requiring cytidine for growth.

Authors:  J Neuhard; J Ingraham
Journal:  J Bacteriol       Date:  1968-06       Impact factor: 3.490

7.  Control of carbamyl phosphate synthesis in Salmonella typhimurium.

Authors:  A Abd-el-Al; J L Ingraham
Journal:  J Biol Chem       Date:  1969-08-10       Impact factor: 5.157

8.  Genetic analysis of pyrimidine mutants of Salmonella typhimurium.

Authors:  Y Yan; M Demerec
Journal:  Genetics       Date:  1965-09       Impact factor: 4.562

9.  Repression of enzyme synthesis of the pyrimidine pathway in Salmonella typhimurium.

Authors:  J C Williams; G A O'Donovan
Journal:  J Bacteriol       Date:  1973-09       Impact factor: 3.490

10.  Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk).

Authors:  C F Beck; J Neuhard; E Thomassen; J L Ingraham; E Kleker
Journal:  J Bacteriol       Date:  1974-12       Impact factor: 3.490
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  9 in total

1.  GIM3E: condition-specific models of cellular metabolism developed from metabolomics and expression data.

Authors:  Brian J Schmidt; Ali Ebrahim; Thomas O Metz; Joshua N Adkins; Bernhard Ø Palsson; Daniel R Hyduke
Journal:  Bioinformatics       Date:  2013-08-23       Impact factor: 6.937

Review 2.  The Emerging Role of Cytidine Deaminase in Human Diseases: A New Opportunity for Therapy?

Authors:  Audrey Frances; Pierre Cordelier
Journal:  Mol Ther       Date:  2019-12-06       Impact factor: 11.454

3.  Effect of pyrophosphate and orotidine monophosphate on cytosine deaminase regulatory properties.

Authors:  T P West
Journal:  Experientia       Date:  1985-12-15

4.  Localization of the codA gene on the Escherichia coli chromosome.

Authors:  E A Austin; B E Huber
Journal:  J Bacteriol       Date:  1993-06       Impact factor: 3.490

Review 5.  Linkage map of Salmonella typhimurium, Edition VI.

Authors:  K E Sanderson; J R Roth
Journal:  Microbiol Rev       Date:  1983-09

6.  Pyrimidine, purine and nitrogen control of cytosine deaminase synthesis in Escherichia coli K 12. Involvement of the glnLG and purR genes in the regulation of codA expression.

Authors:  L Andersen; M Kilstrup; J Neuhard
Journal:  Arch Microbiol       Date:  1989       Impact factor: 2.552

7.  Gene therapeutic approach to primary and metastatic brain tumors: I. CD44 variant pre-RNA alternative splicing as a CEPT control element.

Authors:  D C Asman; J F Dirks; L Ge; N M Resnick; L A Salvucci; J T Gau; M J Becich; D L Cooper; G J Dougherty
Journal:  J Neurooncol       Date:  1995-12       Impact factor: 4.130

8.  Pyrimidine base and ribonucleoside utilization by the Pseudomonas alcaligenes group.

Authors:  T P West
Journal:  Antonie Van Leeuwenhoek       Date:  1991-05       Impact factor: 2.271

9.  Pyrimidine ribonucleoside catabolic enzyme activities of Pseudomonas pickettii.

Authors:  T P West
Journal:  Antonie Van Leeuwenhoek       Date:  1994       Impact factor: 2.271
  9 in total

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