Literature DB >> 3000814

Effect of pyrophosphate and orotidine monophosphate on cytosine deaminase regulatory properties.

T P West.   

Abstract

The maximal velocity of the reaction (Vmax) and the half-saturation constant (K0.5) values of the S. typhimurium cytosine deaminase were altered in the presence of its effectors, pyrophosphate and orotidine monophosphate. From the kinetics of orotidine monophosphate inhibition of cytosine deaminase, it was characterized as a mixed-type noncompetitive inhibitor.

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Year:  1985        PMID： 3000814     DOI： 10.1007/bf01964808

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  10 in total

1.  Purification and properties of orotidylate decarboxylases from yeast and rat liver.

Authors:  W A CREASEY; R E HANDSCHUMACHER
Journal:  J Biol Chem       Date:  1961-07       Impact factor: 5.157

2.  Procedure for the study of certain enzymes in minute amounts and its application to the investigation of cytosine deaminase.

Authors:  E CHARGAFF; J KREAM
Journal:  J Biol Chem       Date:  1948-09       Impact factor: 5.157

3.  Biosynthesis of bacterial glycogen IX: regulatory properties of the adenosine diphosphate glucose pyrophosphrylases of the Enterobacterieae.

Authors:  G Ribéreau-Gayon; A Sabraw; C Lammel; J Preiss
Journal:  Arch Biochem Biophys       Date:  1971-02       Impact factor: 4.013

4.  Baker's yeast cytosine deaminase. Some enzymic properties and allosteric inhibition by nucleosides and nucleotides.

Authors:  P L Ipata; F Marmocchi; G Magni; R Felicioli; G Polidoro
Journal:  Biochemistry       Date:  1971-11       Impact factor: 3.162

5.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

6.  Repression of cytosine deaminase by pyrimidines in Salmonella typhimurium.

Authors:  T P West; G A O'Donovan
Journal:  J Bacteriol       Date:  1982-03       Impact factor: 3.490

7.  Repression of enzyme synthesis of the pyrimidine pathway in Salmonella typhimurium.

Authors:  J C Williams; G A O'Donovan
Journal:  J Bacteriol       Date:  1973-09       Impact factor: 3.490

8.  Physiological factors in the regulation of alkaline phosphatase synthesis in Escherichia coli.

Authors:  A S Wilkins
Journal:  J Bacteriol       Date:  1972-05       Impact factor: 3.490

9.  Salmonella typhimurium mutants defective in cytidine monophosphate kinase (cmk).

Authors:  C F Beck; J Neuhard; E Thomassen; J L Ingraham; E Kleker
Journal:  J Bacteriol       Date:  1974-12       Impact factor: 3.490

10.  Purification and some properties of cytosine deaminase from Salmonella typhimurium.

Authors:  T P West; M S Shanley; G A O'Donovan
Journal:  Biochim Biophys Acta       Date:  1982-11-24
  10 in total

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