| Literature DB >> 7031066 |
G I Tennekoon, J Frangia, S Aitchison, D L Price.
Abstract
This immunohistochemical study describes the localization of the enzyme cerebroside sulfotransferase (phosphoadenosine phosphosulfate: galactosylceramide sulfotransferase, EC 2.8.2.11) in rat kidney. The enzyme was purified from kidney and the preparation was used to raise antibodies for immunocytochemical investigations. In the kidney, the antigen was present only on the brush border of the epithelial cells of the proximal tubules, suggesting that sulfation of glycolipids occurs in the cytoplasm and plasma membranes of these specific cells. Moreover, biochemical and immunocytochemical studies of cerebroside sulfotransferase during development indicate that catalytic activity is correlated with the appearance of enzyme protein.Entities:
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Year: 1981 PMID： 7031066 PMCID： PMC2111977 DOI： 10.1083/jcb.91.2.332
Source DB: PubMed Journal: J Cell Biol ISSN： 0021-9525 Impact factor: 10.539