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Literature DB >> 7029214

Are pyrimidine dimers non-instructive lesions?

Abstract

Published data from yeast and E. coli show that base substitution induced by UV in pyrimidine-pyrimidine sequences is not random, and suggest that fidelity of DNA replication is not entirely lost during transdimer synthesis. These observations question whether cyclobutane pyrimidine dimers are truly non-instructive lesions.

Entities: Chemical Species

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Year: 1981 PMID： 7029214 DOI： 10.1007/bf00293945

Source DB: PubMed Journal: Mol Gen Genet ISSN： 0026-8925

15 in total

1. NUCLEASE-RESISTANT SEQUENCES IN ULTRAVIOLET-IRRADIATED DEOXYRIBONUCLEIC ACID.

Authors: R B SETLOW; W L CARRIER; F J BOLLUM
Journal: Biochim Biophys Acta Date: 1964-11-15

2. The timing of UV mutagenesis in yeast: continuing mutation in an excision-defective (rad1-1) strain.

Authors: A P James; B J Kilbey; G J Prefontaine
Journal: Mol Gen Genet Date: 1978-10-04

3. Molecular basis of base substitution hotspots in Escherichia coli.

Authors: C Coulondre; J H Miller; P J Farabaugh; W Gilbert
Journal: Nature Date: 1978-08-24 Impact factor: 49.962

4. Molecular mechanisms of induced mutagenesis. Replication in vivo of bacteriophage phiX174 single-stranded, ultraviolet light-irradiated DNA in intact and irradiated host cells.

Authors: P Caillet-Fauquet; M Defais; M Radman
Journal: J Mol Biol Date: 1977-11-25 Impact factor: 5.469

5. Specificity and frequency of ultraviolet-induced reversion of an iso-1-cytochrome c ochre mutant in radiation-sensitive strains of yeast.

Authors: C W Lawrence; J W Stewart; F Sherman; R Christensen
Journal: J Mol Biol Date: 1974-05-05 Impact factor: 5.469

6. Genetic studies of the lac repressor. IV. Mutagenic specificity in the lacI gene of Escherichia coli.

Authors: C Coulondre; J H Miller
Journal: J Mol Biol Date: 1977-12-15 Impact factor: 5.469

Review 7. Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli.

Authors: E M Witkin
Journal: Bacteriol Rev Date: 1976-12

8. Genetic studies of the lac repressor. III. Additional correlation of mutational sites with specific amino acid residues.

Authors: C Coulondre; J H Miller
Journal: J Mol Biol Date: 1977-12-15 Impact factor: 5.469

9. On the fidelity of DNA replication. Studies with human placenta DNA polymerases.

Authors: G Seal; C W Shearman; L A Loeb
Journal: J Biol Chem Date: 1979-06-25 Impact factor: 5.157

10. Metabolic suppressors of trimethoprim and ultraviolet light sensitivities of Saccharomyces cerevisiae rad6 mutants.

Authors: C W Lawrence; R B Christensen
Journal: J Bacteriol Date: 1979-09 Impact factor: 3.490

7 in total

1. T-T cyclobutane dimers are misinstructive, rather than non-instructive, mutagenic lesions.

Authors: C W Lawrence; S K Banerjee; A Borden; J E LeClerc
Journal: Mol Gen Genet Date: 1990-06

2. Frequency and spectrum of mutations produced by a single cis-syn thymine-thymine cyclobutane dimer in a single-stranded vector.

Authors: S K Banerjee; R B Christensen; C W Lawrence; J E LeClerc
Journal: Proc Natl Acad Sci U S A Date: 1988-11 Impact factor: 11.205

7. Replication of UV-irradiated single-stranded DNA by DNA polymerase III holoenzyme of Escherichia coli: evidence for bypass of pyrimidine photodimers.

Authors: Z Livneh
Journal: Proc Natl Acad Sci U S A Date: 1986-07 Impact factor: 11.205