Literature DB >> 7024909

Yeast ochre suppressor SUQ5-ol is an altered tRNA Ser UCA.

C Waldron, B S Cox, N Wills, R F Gesteland, P W Piper, D Colby, C Guthrie.   

Abstract

Ochre suppressor tRNA was partially purified from strains of Saccharomyces cerevisiae containing the serine-inserting class III suppressor SUQ5-ol. RNA sequence analysis of this tRNA indicated that the suppressor is derived from a UCA-decoding tRNA Ser by a G leads to U substitution in the middle position of the anticodon. The suppressor further differs from the wild-type UCA-decoding tRNA Ser in that the mutant anticodon lacks the modified uridine found in the wobble position of the wild-type tRNA and contains instead another modification in or near the anticodon.

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Year:  1981        PMID： 7024909      PMCID： PMC327332          DOI： 10.1093/nar/9.13.3077

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN： 0305-1048            Impact factor:   16.971


  17 in total

1.  Mapping of yeast tRNAs by two-dimensional electrophoresis on polyacrylamide gels.

Authors:  A Fradin; H Gruhl; H Feldmann
Journal:  FEBS Lett       Date:  1975-02-01       Impact factor: 4.124

2.  Serine substitutions caused by an ochre suppressor in yeast.

Authors:  S W Liebman; J W Stewart; F Sherman
Journal:  J Mol Biol       Date:  1975-06-05       Impact factor: 5.469

3.  Enhanced differential synthesis of proteins in a mammalian cell-free system by addition of polyamines.

Authors:  J F Atkins; J B Lewis; C W Anderson; R F Gesteland
Journal:  J Biol Chem       Date:  1975-07-25       Impact factor: 5.157

4.  Yeast suppressors of UAA and UAG nonsense codons work efficiently in vitro via tRNA.

Authors:  R F Gesteland; M Wolfner; P Grisafi; G Fink; D Botstein; J R Roth
Journal:  Cell       Date:  1976-03       Impact factor: 41.582

5.  Nucleotide sequence of a mutant eukaryotic gene: the yeast tyrosine-inserting ochre suppressor SUP4-o.

Authors:  H M Goodman; M V Olson; B D Hall
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

6.  The nucleotide sequence of Saccharomyces cerevisiae 5.8 S ribosomal ribonucleic acid.

Authors:  G M Rubin
Journal:  J Biol Chem       Date:  1973-06-10       Impact factor: 5.157

7.  Isolation and characterization of 2-methyladenosine from Escherichia coli tRNA Glu 2 , tRNA Asp 1 , tRNA His 1 and tRNA Arg .

Authors:  M Saneyoshi; Z Oashi; F Harada; S Nishimura
Journal:  Biochim Biophys Acta       Date:  1972-02-23

8.  Improved separation of transfer RNA's on polychlorotrifuoroethylene-supported reversed-phase chromatography columns.

Authors:  R L Pearson; J F Weiss; A D Kelmers
Journal:  Biochim Biophys Acta       Date:  1971-02-11

9.  Separation of transfer ribonucleic acid by sepharose chromatography using reverse salt gradients.

Authors:  W M Holmes; R E Hurd; B R Reid; R A Rimerman; G W Hatfield
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205

10.  Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon.

Authors:  P W Piper; M Wasserstein; F Engbaek; K Kaltoft; J E Celis; J Zeuthen; S Liebman; F Sherman
Journal:  Nature       Date:  1976-08-26       Impact factor: 49.962
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  12 in total

Review 1.  Thionucleosides in transfer ribonucleic acid: diversity, structure, biosynthesis, and function.

Authors:  P Ajitkumar; J D Cherayil
Journal:  Microbiol Rev       Date:  1988-03

2.  Undermodification in the first position of the anticodon of supG-tRNA reduces translational efficiency.

Authors:  T G Hagervall; G R Björk
Journal:  Mol Gen Genet       Date:  1984

3.  Enzymatic replacement in vitro of the first anticodon base of yeast tRNAAsp: application to the study of tRNA maturation in vivo, after microinjection into frog oocytes.

Authors:  P Carbon; E Haumont; S De Henau; G Keith; H Grosjean
Journal:  Nucleic Acids Res       Date:  1982-06-25       Impact factor: 16.971

Review 4.  Informational suppression as a tool for the investigation of gene structure and function.

Authors:  R E Glass; V Nene; M G Hunter
Journal:  Biochem J       Date:  1982-04-01       Impact factor: 3.857

5.  Saccharomyces cerevisiae Hsp70 mutations affect [PSI+] prion propagation and cell growth differently and implicate Hsp40 and tetratricopeptide repeat cochaperones in impairment of [PSI+].

Authors:  Gary W Jones; Daniel C Masison
Journal:  Genetics       Date:  2003-02       Impact factor: 4.562

6.  Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough.

Authors:  Jason W Harger; Jonathan D Dinman
Journal:  RNA       Date:  2004-09-23       Impact factor: 4.942

7.  Regulation of release factor expression using a translational negative feedback loop: a systems analysis.

Authors:  Russell Betney; Eric de Silva; Christina Mertens; Yvonne Knox; J Krishnan; Ian Stansfield
Journal:  RNA       Date:  2012-10-25       Impact factor: 4.942

8.  A mutant allele of the SUP45 (SAL4) gene of Saccharomyces cerevisiae shows temperature-dependent allosuppressor and omnipotent suppressor phenotypes.

Authors:  I Stansfield; M F Tuite
Journal:  Curr Genet       Date:  1995-04       Impact factor: 3.886

9.  In vitro nonsense suppression in [psi+] and [psi-] cell-free lysates of Saccharomyces cerevisiae.

Authors:  M F Tuite; B S Cox; C S McLaughlin
Journal:  Proc Natl Acad Sci U S A       Date:  1983-05       Impact factor: 11.205

10.  Prion-dependent lethality of sup45 mutants in Saccharomyces cerevisiae.

Authors:  Denis Kiktev; Sergey Inge Vechtomov; Galina Zhouravleva
Journal:  Prion       Date:  2007-04-04       Impact factor: 3.931
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