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Literature DB >> 7023488

Mechanism of nifurtimox toxicity in different forms of Trypanosoma cruzi.

R Docampo, S N Moreno, A O Stoppani, W Leon, F S Cruz, F Villalta, R F Muniz.

Abstract

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1981 PMID： 7023488 DOI： 10.1016/0006-2952(81)90204-5

Source DB: PubMed Journal: Biochem Pharmacol ISSN： 0006-2952 Impact factor: 5.858

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12 in total

1. Buthionine sulfoximine increases the toxicity of nifurtimox and benznidazole to Trypanosoma cruzi.

Authors: Mario Faundez; Laura Pino; Paula Letelier; Carla Ortiz; Rodrigo López; Claudia Seguel; Jorge Ferreira; Mario Pavani; Antonio Morello; Juan Diego Maya
Journal: Antimicrob Agents Chemother Date: 2005-01 Impact factor: 5.191

2. Induction of oxidative stress in Trypanosoma brucei by the antitrypanosomal dihydroquinoline OSU-40.

Authors: Shanshan He; Alex Dayton; Periannan Kuppusamy; Karl A Werbovetz; Mark E Drew
Journal: Antimicrob Agents Chemother Date: 2012-02-06 Impact factor: 5.191

3. Putrescine analogue cytotoxicity against Trypanosoma cruzi.

Authors: D Menezes; C Valentim; M F Oliveira; M A Vannier-Santos
Journal: Parasitol Res Date: 2005-11-11 Impact factor: 2.289

4. New method for quantification of Trypanosoma cruzi in animal's tissue in the chronic phase of experimental Chagas' disease.

Authors: Viviane Rodrigues Esperandim; Daniele da Silva Ferreira; Miriam Paula Alonso Toldo; Juliana Saraiva; Mariana Bryan Augusto; Sérgio de Albuquerque
Journal: Parasitol Res Date: 2010-02-23 Impact factor: 2.289

5. A new pharmacological screening assay with Trypanosoma cruzi epimastigotes expressing beta-galactosidase.

Authors: C Vega; M Rolón; A R Martínez-Fernández; J A Escario; A Gómez-Barrio
Journal: Parasitol Res Date: 2005-01-29 Impact factor: 2.289

6. TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum.

Authors: Shane R Wilkinson; Martin C Taylor; Said Touitha; Isabel L Mauricio; David J Meyer; John M Kelly
Journal: Biochem J Date: 2002-06-15 Impact factor: 3.857

Mechanism of nifurtimox toxicity in different forms of Trypanosoma cruzi.

1. Buthionine sulfoximine increases the toxicity of nifurtimox and benznidazole to Trypanosoma cruzi.

2. Induction of oxidative stress in Trypanosoma brucei by the antitrypanosomal dihydroquinoline OSU-40.

3. Putrescine analogue cytotoxicity against Trypanosoma cruzi.

4. New method for quantification of Trypanosoma cruzi in animal's tissue in the chronic phase of experimental Chagas' disease.

5. A new pharmacological screening assay with Trypanosoma cruzi epimastigotes expressing beta-galactosidase.

6. TcGPXII, a glutathione-dependent Trypanosoma cruzi peroxidase with substrate specificity restricted to fatty acid and phospholipid hydroperoxides, is localized to the endoplasmic reticulum.

7. The development of drugs for treatment of sleeping sickness: a historical review.

8. Activity of megazol, a trypanocidal nitroimidazole, is associated with DNA damage.

9. Evaluating 5-nitrofurans as trypanocidal agents.

10. Effect of tingenone, a quinonoid triterpene, on growth and macromolecule biosynthesis in Trypanosoma cruzi.