Literature DB >> 702056

A macrophage tumor cell line and plasminogen activator. A potential model system for macrophage regulation of enzyme production.

J A Hamilton, P Ralph, M A Moore.   

Abstract

The macrophage cell line, RAW264.10, synthesizes and secretes plasminogen activator. Production of this enzyme is inhibited by low concentrations of glucocorticoids and increased by phorbol myristate acetate. It is proposed that this line could be a suitable model for the regulation of enzyme synthesis by mouse peritoneal macrophages.

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Year:  1978        PMID： 702056      PMCID： PMC2185004          DOI： 10.1084/jem.148.3.811

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  12 in total

1.  Antibody-dependent killing of erythrocyte and tumor targets by macrophage-related cell lines: enhancement by PPD and LPS.

Authors:  P Ralph; I Nakoinz
Journal:  J Immunol       Date:  1977-09       Impact factor: 5.422

2.  Relative merits of the adreno-cortical steroids.

Authors:  D H NELSON
Journal:  Annu Rev Med       Date:  1962       Impact factor: 13.739

3.  Macrophage plasminogen activator: induction by concanavalin A and phorbol myristate acetate.

Authors:  J D Vassalli; J Hamilton; E Reich
Journal:  Cell       Date:  1977-07       Impact factor: 41.582

4.  Activation of Hageman factor in solid and fluid phases. A critical role of kallikrein.

Authors:  C G Cochrane; S D Revak; K D Wuepper
Journal:  J Exp Med       Date:  1973-12-01       Impact factor: 14.307

5.  Secretion of plasminogen activator by stimulated macrophages.

Authors:  J C Unkeless; S Gordon; E Reich
Journal:  J Exp Med       Date:  1974-04-01       Impact factor: 14.307

6.  The conversion of C'IS to C'1 esterase by plasmin and trypsin.

Authors:  O D Ratnoff; G B Naff
Journal:  J Exp Med       Date:  1967-02-01       Impact factor: 14.307

7.  Macrophage plasminogen activator: induction by asbestos is blocked by anti-inflammatory steroids.

Authors:  J Hamilton; J D Vassalli; E Reich
Journal:  J Exp Med       Date:  1976-12-01       Impact factor: 14.307

8.  Macrophage plasminogen activator: induction by products of activated lymphoid cells.

Authors:  J D Vassalli; E Reich
Journal:  J Exp Med       Date:  1977-02-01       Impact factor: 14.307

9.  A prealbumin activator of prekallikrein. II. Derivation of activators of prekallikrein from active Hageman factor by digestion with plasmin.

Authors:  A P Kaplan; K F Austen
Journal:  J Exp Med       Date:  1971-04-01       Impact factor: 14.307

10.  Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.

Authors:  J I Kurland; R Bockman
Journal:  J Exp Med       Date:  1978-03-01       Impact factor: 14.307
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