| Literature DB >> 7018855 |
M A Gerosa, E di Stefano, A Olivi, A Carteri.
Abstract
A 5-year experience of the multidisciplinary treatment of pediatric medulloblastoma with the SIOP (International Society of Pediatric Oncology) trial is presented. 33 eligible patients finally reduced to a total of 30 evaluative cases were treated with major surgical resection, extensive irradiation, and combined chemotherapy (vincristine + CCNU). The overall survival rate without recurrence was encouraging, and the actuarial survival rate is satisfactory. At follow-up controls, most of the patients showed a good performance status and a promising neurological stage. However, the problem concerning quality of life remains unsolved: morbidity and sequelae following high-dose radiotherapy and concomitant antiblastic treatment were noticeable.Entities:
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Year: 1981 PMID： 7018855 DOI： 10.1159/000119972
Source DB: PubMed Journal: Childs Brain ISSN： 0302-2803