Literature DB >> 7018159

Experimental allergic encephalomyelitis. Exsudate and cellular infiltrates in the spinal cord of Lewis rats.

H P Ackermann, J Ulrich, P U Heitz.   

Abstract

Classical acute allergic encephalomyelitis (EAE) was provoked in Lewis rats with bovine spinal cord (BWM) in complete Freund's adjuvant (CFA). An efficient immunohistologic technique (peroxidase-antiperoxidase (PAP) was used to trace exsudates of fibrinogen and immunoglobulin as well as their coexistence with cellular infiltrates and clinical signs. Exsudation was restricted to the vessels exhibiting cellular infiltrates. The findings do not lend support to the assumption that exsudation of circulating factors is the initial local event in EAE. It also remains open, whether the exsudation of fibrinogen and gamma globulin are responsible for the clinical symptoms.

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Year:  1981        PMID： 7018159     DOI： 10.1007/bf00689408

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN： 0001-6322            Impact factor:   17.088


  14 in total

1.  ELECTRON MICROSCOPIC STUDIES ON THE VASCULAR PERMEABILITY AND THE MECHANISM OF DEMYELINATION IN EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS.

Authors:  P LAMPERT; S CARPENTER
Journal:  J Neuropathol Exp Neurol       Date:  1965-01       Impact factor: 3.685

2.  A histologic study of the early lesion in experimental allergic encephalomyelitis in the guinea pig and rabbit.

Authors:  B H WAKSMAN; R D ADAMS
Journal:  Am J Pathol       Date:  1962-08       Impact factor: 4.307

3.  Tuberculin type sensitivity to spinal cord antigen in rabbits with isoallergic encephalomyelitis.

Authors:  B H WAKSMAN; L R MORRISON
Journal:  J Immunol       Date:  1951-04       Impact factor: 5.422

4.  Experimental allergic encephalomyelitis--migration of early T cells from the circulation into the central nervous system.

Authors:  U Traugott; S H Stone; C S Raine
Journal:  J Neurol Sci       Date:  1978-03       Impact factor: 3.181

5.  Brain vascular permeability to I-125 gamma globulin and leukocytes in allergic encephalomyelitis.

Authors:  R W Cutler; A V Lorenzo; C F Barlow
Journal:  J Neuropathol Exp Neurol       Date:  1967-10       Impact factor: 3.685

6.  Cerebral vascular permeability and cellular infiltration in experimental allergic encephalomyelitis.

Authors:  S Leibowitz; L Kennedy
Journal:  Immunology       Date:  1972-05       Impact factor: 7.397

7.  Experimental allergic encephalomyelitis: role of fibrin deposition in immunopathogenesis of inflammation in rats.

Authors:  P Y Paterson
Journal:  Fed Proc       Date:  1976-11

8.  Inhibition of experimental allergic encephalomyelitis in rats severely depleted of T cells.

Authors:  N K Gonatas; J C Howard
Journal:  Science       Date:  1974-11-29       Impact factor: 47.728

9.  The significance of circulating and cell-bound antibodies in experimental allergic encephalomyelitis.

Authors:  N K Gonatas; J O Gonatas; A Stieber; R Lisak; K Suzuki; R E Martenson
Journal:  Am J Pathol       Date:  1974-09       Impact factor: 4.307

10.  Transfer of allergic encephalomyelitis in rats by means of lymph node cells.

Authors:  P Y PATERSON
Journal:  J Exp Med       Date:  1960-01-01       Impact factor: 14.307
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  2 in total

1.  Simultaneous visualization of vascular permeability change and leukocyte egress in the central nervous system during autoimmune encephalomyelitis.

Authors:  R D Simmons; T M Buzbee; D S Linthicum; W J Mandy; G Chen; C Wang
Journal:  Acta Neuropathol       Date:  1987       Impact factor: 17.088

2.  Blood-nerve barrier studies in experimental allergic neuritis.

Authors:  A F Hahn; T E Feasby; J J Gilbert
Journal:  Acta Neuropathol       Date:  1985       Impact factor: 17.088
  2 in total

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