Literature DB >> 701275

Peroxisomal localization of serine:pyruvate aminotransferase in human liver.

T Noguchi, Y Takada.   

Abstract

The distribution of L-serine:pyruvate aminotransferase (EC 2.6.1.51) in human liver was examined by centrifugation in a sucrose density gradient. The enzyme was located only in the peroxisomes and in the soluble fraction. The peroxisomal and soluble enzymes were highly purified and characterized. The two enzyme preparations had nearly identical properties, suggesting that the soluble enzyme is from broken peroxisomes. The two enzyme preparations showed different properties from rat liver serine:pyruvate aminotransferase (Noguchi, T., Okuno, E., and Kido, R. (1976) Biochem. J. 159, 607-613).

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Year:  1978        PMID： 701275

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  14 in total

1.  Effect of scrapie incubation on the concentrations of plasma amino acids and L-lactate in infected lambs.

Authors:  G G Allison; P Rees Stevens; L Heasman; A M Davis; R Jackman; J M Moorby
Journal:  Vet Res Commun       Date:  2008-06-12       Impact factor: 2.459

Review 2.  Recent advances in the understanding, diagnosis and treatment of primary hyperoxaluria type 1.

Authors:  C J Danpure
Journal:  J Inherit Metab Dis       Date:  1989       Impact factor: 4.982

3.  Immunocytochemical localization of serine: pyruvate aminotransferase in peroxisomes of the human liver parenchymal cells.

Authors:  S Yokota; T Oda; A Ichiyama
Journal:  Histochemistry       Date:  1987

4.  Carnitine acyltransferase and acyl-coenzyme A hydrolase activities in human liver. Quantitative analysis of their subcellular localization.

Authors:  M Bronfman; F Leighton
Journal:  Biochem J       Date:  1984-12-15       Impact factor: 3.857

5.  The subcellular distribution of alanine-glyoxylate aminotransferase and serine-pyruvate aminotransferase in dog liver.

Authors:  E Okuno; Y Minatogawa; J Nakanishi; M Nakamura; N Kamoda; M Makino; R Kido
Journal:  Biochem J       Date:  1979-09-15       Impact factor: 3.857

Review 6.  The role of peroxisomes in mammalian cellular metabolism.

Authors:  P B Lazarow
Journal:  J Inherit Metab Dis       Date:  1987       Impact factor: 4.982

7.  Evolution of alanine:glyoxylate aminotransferase intracellular targeting: structural and functional analysis of the guinea pig gene.

Authors:  G M Birdsey; C J Danpure
Journal:  Biochem J       Date:  1998-04-01       Impact factor: 3.857

8.  Enzymological and mutational analysis of a complex primary hyperoxaluria type 1 phenotype involving alanine:glyoxylate aminotransferase peroxisome-to-mitochondrion mistargeting and intraperoxisomal aggregation.

Authors:  C J Danpure; P E Purdue; P Fryer; S Griffiths; J Allsop; M J Lumb; K M Guttridge; P R Jennings; J I Scheinman; S M Mauer
Journal:  Am J Hum Genet       Date:  1993-08       Impact factor: 11.025

9.  Acyl-CoA synthetase and the peroxisomal enzymes of beta-oxidation in human liver. Quantitative analysis of their subcellular localization.

Authors:  M Bronfman; N C Inestrosa; F O Nervi; F Leighton
Journal:  Biochem J       Date:  1984-12-15       Impact factor: 3.857

10.  Crystallization and characterization of human liver kynurenine--glyoxylate aminotransferase. Identity with alanine--glyoxylate aminotransferase and serine--pyruvate aminotransferase.

Authors:  E Okuno; Y Minatogawa; M Nakamura; N Kamoda; J Nakanishi; M Makino; R Kido
Journal:  Biochem J       Date:  1980-09-01       Impact factor: 3.857
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