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Literature DB >> 7011613

Characterization of facteur thymique sérique (FTS) in the thymus. II. Direct demonstration of the presence of FTS in thymosin fraction V.

M Dardenne, J M Pléau, J Y Blouquit, J F Bach.

Abstract

Thymosin fraction V was submitted to the same purification procedure as used for the isolation of the circulating thymic factor (FTS) from pig serum: an FTS-like material was isolated from this fraction and shown to have similar activity, molecular weight, charge and amino acid composition as FTS. These data, together with previous experiments showing the binding of anti-FTS antibodies to reticulo-epithelial cells, provide a direct argument in favour of the presence of FTS in the thymus.

Entities: Chemical Species

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Year: 1980 PMID： 7011613 PMCID： PMC1537161

Source DB: PubMed Journal: Clin Exp Immunol ISSN： 0009-9104 Impact factor: 4.330

7 in total

1. The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin alpha1 and polypeptide beta1 from calf thymus.

Authors: T L Low; G B Thurman; M McAdoo; J McClure; J L Rossio; P H Naylor; A L Goldstein
Journal: J Biol Chem Date: 1979-02-10 Impact factor: 5.157

2. Protein measurement with the Folin phenol reagent.

Authors: O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal: J Biol Chem Date: 1951-11 Impact factor: 5.157

3. Purification and properties of bovine thymosin.

Authors: J A Hooper; M C McDaniel; G B Thurman; G H Cohen; R S Schulof; A L Goldstein
Journal: Ann N Y Acad Sci Date: 1975-02-28 Impact factor: 5.691

4. T-lymphocyte maturation: cell surface markers and immune function induced by T-lymphocyte cell-free products and thymosin polypeptides.

Authors: A Ahmed; D M Wong; G B Thurman; T L Low; A L Goldstein; S J Sharkis; I Goldschneider
Journal: Ann N Y Acad Sci Date: 1979 Impact factor: 5.691

5. Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone.

Authors: J F Bach; M Dardenne; A L Goldstein; A Guha; A White
Journal: Proc Natl Acad Sci U S A Date: 1971-11 Impact factor: 11.205

6. Structural study of circulating thymic factor: a peptide isolated from pig serum. I. Isolation and purification.

Authors: M Dardenne; J M Pleau; N K Man; J F Bach
Journal: J Biol Chem Date: 1977-11-25 Impact factor: 5.157

7. Characterization of facteur thymique sérique (FTS) in the thymus. I. Fixation of anti-FTS antibodies on thymic reticulo-epithelial cells.

Authors: J C Monier; M Dardenne; J M Pléau; D Schmitt; P Deschaux; J F Bach
Journal: Clin Exp Immunol Date: 1980-12 Impact factor: 4.330

7 in total

7. Thymic hormone-containing cells. Characterization and localization of serum thymic factor in young mouse thymus studied by monoclonal antibodies.

Authors: W Savino; M Dardenne; M Papiernik; J F Bach
Journal: J Exp Med Date: 1982-08-01 Impact factor: 14.307

7 in total

Characterization of facteur thymique sérique (FTS) in the thymus. II. Direct demonstration of the presence of FTS in thymosin fraction V.

1. The chemistry and biology of thymosin. I. Isolation, characterization, and biological activities of thymosin alpha1 and polypeptide beta1 from calf thymus.

2. Protein measurement with the Folin phenol reagent.

3. Purification and properties of bovine thymosin.

4. T-lymphocyte maturation: cell surface markers and immune function induced by T-lymphocyte cell-free products and thymosin polypeptides.

5. Appearance of T-cell markers in bone marrow rosette-forming cells after incubation with thymosin, a thymic hormone.

6. Structural study of circulating thymic factor: a peptide isolated from pig serum. I. Isolation and purification.

7. Characterization of facteur thymique sérique (FTS) in the thymus. I. Fixation of anti-FTS antibodies on thymic reticulo-epithelial cells.

1. The serum thymic factor (FTS). Chemical and biological aspects.

2. Contribution of zinc and other metals to the biological activity of the serum thymic factor.

3. Generation of a monoclonal antibody against facteur thymique serique (FTS).

4. Effect of synthetic thymic humoral factor (THF-gamma 2) on T cell activities in immunodeficient ageing mice.

5. Localization of zinc in the thymic reticulum of mice by electron-probe microanalysis.

6. Thymodepressin-Unforeseen Immunosuppressor.

7. Thymic hormone-containing cells. Characterization and localization of serum thymic factor in young mouse thymus studied by monoclonal antibodies.