Literature DB >> 303241

Structural study of circulating thymic factor: a peptide isolated from pig serum. I. Isolation and purification.

M Dardenne, J M Pleau, N K Man, J F Bach.   

Abstract

A circulating thymic factor (FTS) has been characterized by a bioassay based on its ability to render theta-negative rosette-forming cells theta-positive and azathioprine-sensitive. FTS was sequentially purified and finally isolated from 1000 liters of pig serum by ultrafiltration, gel filtration, and ion exchange chromatography. Its amino acid composition and apparent molecular weight estimated by Sephadex G-25 chromatography, indicate that FTS is a nonapeptide of composition lysine, aspartic acid (or asparagine), serine 2, glutamic acid (or glutamine) 2, glycine 2, and alanine.

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Year:  1977        PMID： 303241

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  13 in total

1.  Immunohistochemical characterization of the thymic microenvironment. A light-microscopic and ultrastructural immunocytochemical study.

Authors:  B von Gaudecker; G G Steinmann; M L Hansmann; J Harpprecht; N M Milicevic; H K Müller-Hermelink
Journal:  Cell Tissue Res       Date:  1986       Impact factor: 5.249

Review 2.  Thymic hormones--a clinical update.

Authors:  M B Sztein; A L Goldstein
Journal:  Springer Semin Immunopathol       Date:  1986

3.  The serum thymic factor (FTS). Chemical and biological aspects.

Authors:  J M Pleau; M Dardenne; J F Bach
Journal:  Mol Cell Biochem       Date:  1981-12-04       Impact factor: 3.396

4.  Isolation and characterization of DNA-binding peptides from the serum: inhibition of transcription and comparison with the tissue peptides.

Authors:  D Amici; D Barra; M Hillar; O Murri; F Cicconi; G L Gianfranceschi
Journal:  Mol Biol Rep       Date:  1982-11-30       Impact factor: 2.316

5.  Relationship between a spleen-derived immunosuppressive peptide 'SDIP' and the 'Facteur thymique sérique' (FTS): biochemical and biological comparison of the two factors.

Authors:  M Lenfant; L Millerioux; I Blazsek; N Duchange
Journal:  Immunology       Date:  1983-04       Impact factor: 7.397

6.  Specific receptors for the serum thymic factor (FTS) in lymphoblastoid cultured cell lines.

Authors:  J M Pléau; V Fuentes; J L Morgat; J F Bach
Journal:  Proc Natl Acad Sci U S A       Date:  1980-05       Impact factor: 11.205

7.  Characterization of facteur thymique sérique (FTS) in the thymus. I. Fixation of anti-FTS antibodies on thymic reticulo-epithelial cells.

Authors:  J C Monier; M Dardenne; J M Pléau; D Schmitt; P Deschaux; J F Bach
Journal:  Clin Exp Immunol       Date:  1980-12       Impact factor: 4.330

8.  In vitro induction of monoclonal antibody-defined T-cell markers in lymphocytes from immunodeficient children by synthetic serum thymic factor (FTS).

Authors:  M C Bene; G Faure; P Bordigoni; D Olive; J Duheille
Journal:  Clin Exp Immunol       Date:  1982-05       Impact factor: 4.330

9.  Generation of a monoclonal antibody against facteur thymique serique (FTS).

Authors:  K Ohga; G S Incefy; C Y Wang; R A Good
Journal:  Clin Exp Immunol       Date:  1982-03       Impact factor: 4.330

10.  Enhancement of interleukin-2 and gamma-interferon production in vitro on cord blood lymphocytes and in vivo on primary cellular immunodeficiency patients with thymic extract (thymostimulin).

Authors:  C Y Lin; Y C Kuo; C C Lin; B R Ou
Journal:  J Clin Immunol       Date:  1988-03       Impact factor: 8.317
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