Literature DB >> 7010182

Structure of the neuraminidase gene in human influenza virus A/PR/8/34.

S Fields, G Winter, G G Brownlee.   

Abstract

The complete structure of the neuraminidase gene in influenza A/PR/8/34 has been determined by cloning into the bacteriophage M13 and sequencing with dideoxynucleotide chain terminators. The gene is 1,413 nucleotides long, codes for a protein of 454 amino acids and has five potential glycosylation sites. We suggest that the neuraminidase, unlike the influenza haemagglutinin, is oriented with its N-terminus buried in the viral membrane.

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Year:  1981        PMID： 7010182     DOI： 10.1038/290213a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  62 in total

1.  Sequence of the Lyb-2 B-cell differentiation antigen defines a gene superfamily of receptors with inverted membrane orientation.

Authors:  E Nakayama; I von Hoegen; J R Parnes
Journal:  Proc Natl Acad Sci U S A       Date:  1989-02       Impact factor: 11.205

2.  The major 85-kDa surface antigen of the mammalian-stage forms of Trypanosoma cruzi is a family of sialidases.

Authors:  S Kahn; T G Colbert; J C Wallace; N A Hoagland; H Eisen
Journal:  Proc Natl Acad Sci U S A       Date:  1991-05-15       Impact factor: 11.205

3.  Amino acids bracketing the predicted transmembrane domains of membrane proteins.

Authors:  C Pidgeon; R L Williard; S C Schroeder
Journal:  Pharm Res       Date:  1989-09       Impact factor: 4.200

4.  Immunogenic peptides of influenza virus subtype N1 neuraminidase identify a T-cell determinant used in class II major histocompatibility complex-restricted responses to infectious virus.

Authors:  C J Hackett; D Horowitz; M Wysocka; L C Eisenlohr
Journal:  J Virol       Date:  1991-02       Impact factor: 5.103

Review 5.  Engineering soluble major histocompatibility molecules: why and how.

Authors:  D H Margulies; R Lopez; L F Boyd; J McCluskey
Journal:  Immunol Res       Date:  1987       Impact factor: 2.829

6.  Complete nucleotide sequence of the neuraminidase gene of the human influenza virus A/Chile/1/83 (H1N1). Brief report.

Authors:  E Schreier; H Roeske; G Driesel; U Künkel; D R Petzold; R Berlinghoff; S Michel
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

7.  Evidence for the loop model of signal-sequence insertion into the endoplasmic reticulum.

Authors:  A S Shaw; P J Rottier; J K Rose
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

8.  Human sera possess a limited antibody repertoire to influenza neuraminidase antigenic variants selected in vitro.

Authors:  A Natali; P F Panizzi; C Chezzi; J S Oxford
Journal:  J Hyg (Lond)       Date:  1984-04

9.  NH2-terminal hydrophobic region of influenza virus neuraminidase provides the signal function in translocation.

Authors:  T J Bos; A R Davis; D P Nayak
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

10.  Glycosylation and surface expression of the influenza virus neuraminidase requires the N-terminal hydrophobic region.

Authors:  L Markoff; B C Lin; M M Sveda; C J Lai
Journal:  Mol Cell Biol       Date:  1984-01       Impact factor: 4.272
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