Literature DB >> 7010180

Homology and concerted evolution at the alpha 1 and alpha 2 loci of human alpha-globin.

S A Liebhaber, M Goossens, Y W Kan.   

Abstract

The identical structure of two racially distinct alpha 1-globin alleles and the high degree of homology between the alpha 1- and alpha 2-globin loci indicate that mechanisms exist for suppression of allelic polymorphisms and for exchange of genetic information within the alpha-globin gene complex.

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Year:  1981        PMID: 7010180     DOI: 10.1038/290026a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  90 in total

1.  Rapid, accurate genotyping of the common -alpha(4.2) thalassaemia deletion based on the use of denaturing HPLC.

Authors:  H Ou-Yang; L Hua; Q H Mo; X M Xu
Journal:  J Clin Pathol       Date:  2004-02       Impact factor: 3.411

2.  The primary transcription unit of the human alpha 2 globin gene defined by quantitative RT/PCR.

Authors:  C M Owczarek; P Enriquez-Harris; N J Proudfoot
Journal:  Nucleic Acids Res       Date:  1992-02-25       Impact factor: 16.971

3.  Extent and high frequency of a short conversion between the human A gamma and G gamma fetal globin genes.

Authors:  J Starck; R Bouhass; F Morlé; J Godet
Journal:  Hum Genet       Date:  1990-01       Impact factor: 4.132

4.  Linkage disequilibrium due to random genetic drift in finite subdivided populations.

Authors:  T Ohta
Journal:  Proc Natl Acad Sci U S A       Date:  1982-03       Impact factor: 11.205

5.  Inactivation of human alpha-globin gene expression by a de novo deletion located upstream of the alpha-globin gene cluster.

Authors:  S A Liebhaber; E U Griese; I Weiss; F E Cash; H Ayyub; D R Higgs; J Horst
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

6.  Short gene conversions in the human fetal globin gene region: a by-product of chromosome pairing during meiosis?

Authors:  P A Powers; O Smithies
Journal:  Genetics       Date:  1986-02       Impact factor: 4.562

7.  Leftward deletion alpha-thalassaemia in the Saudi Arabian population.

Authors:  M A el-Hazmi
Journal:  Hum Genet       Date:  1986-11       Impact factor: 4.132

8.  Translational profiles of alpha 1-, alpha 2-, and beta-globin messenger ribonucleic acids in human reticulocytes.

Authors:  S H Shakin; S A Liebhaber
Journal:  J Clin Invest       Date:  1986-10       Impact factor: 14.808

9.  Compensatory increase in alpha 1-globin gene expression in individuals heterozygous for the alpha-thalassemia-2 deletion.

Authors:  S A Liebhaber; F E Cash; D M Main
Journal:  J Clin Invest       Date:  1985-09       Impact factor: 14.808

10.  Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats.

Authors:  J C Schimenti; C H Duncan
Journal:  Nucleic Acids Res       Date:  1984-02-10       Impact factor: 16.971

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