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Literature DB >> 6322113

Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats.

Abstract

Bovine fetal and adult globin genes were cloned and subjected to DNA sequence analysis. Both of these genes contained insertions of Alu-type repetitive DNA within their introns. Comparison of cow and goat beta-type globin genes indicates that intragenic DNA insertions played a role in their evolution. These data support the theory that Alu-type repeats maintain genetic diversity by inhibiting gene conversion.

Entities: Gene Species

Mesh：

Substances：

Year: 1984 PMID： 6322113 PMCID： PMC318605 DOI： 10.1093/nar/12.3.1641

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

65 in total

1. A comparison of amino acid sequences in the beta-chains of adult bovine hemoglobins A and B.

Authors: W A Schroeder; J R Shelton; J B Shelton; B Robberson; D R Babin
Journal: Arch Biochem Biophys Date: 1967-04 Impact factor: 4.013

2. Amino acid sequences in the -chains of adult bovine hemoglobins C-Rhodesia and D-Zambia.

Authors: W A Schroeder; J R Shelton; J B Shelton; G Apell; T H Huisman; L L Smith; W R Carr
Journal: Arch Biochem Biophys Date: 1972-09 Impact factor: 4.013

3. Embryonic and fetal hemoglobin in animals.

Authors: H Kitchen; I Brett
Journal: Ann N Y Acad Sci Date: 1974-11-29 Impact factor: 5.691

4. The in vivo production of hemoglobin C in ruminants.

Authors: T H Huisman
Journal: Ann N Y Acad Sci Date: 1974-11-29 Impact factor: 5.691

5. The synthesis of haemoglobins A and F in the calf.

Authors: W Nijhof; G J Ronda; J H Jonxis
Journal: Biol Neonate Date: 1972

6. The formation of foetal and adult haemoglobin in cell cultures of neonatal calf marrow.

Authors: T G Gabuzda; R K Silver; L C Chui; H B Lewis
Journal: Br J Haematol Date: 1970-11 Impact factor: 6.998

7. Molecular evolution of myoglobin and the fossil record: a phylogenetic synthesis.

Authors: A E Romero-Herrera; H Lehmann; K A Joysey; A E Friday
Journal: Nature Date: 1973-12-14 Impact factor: 49.962

8. The amino acid sequence of the gamma chain of bovine fetal hemoglobin.

Authors: D R Babin; W A Schroeder; J R Shelton; J B Shelton; B Robberson
Journal: Biochemistry Date: 1966-04 Impact factor: 3.162

9. Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene.

Authors: N Maeda; J B Bliska; O Smithies
Journal: Proc Natl Acad Sci U S A Date: 1983-08 Impact factor: 11.205

10. Gene conversion of deletions in the his4 region of yeast.

Authors: G R Fink; C A Styles
Journal: Genetics Date: 1974-06 Impact factor: 4.562

25 in total

1. Remarkably high rate of molecular evolution of ruminant placental lactogens.

Authors: M Wallis
Journal: J Mol Evol Date: 1993-07 Impact factor: 2.395

2. DNA sequence of a class I pseudogene from the Tla region of the murine MHC: recombination at a B2 alu repetitive sequence.

Authors: D A Fisher; M Pecht; L Hood
Journal: J Mol Evol Date: 1989-04 Impact factor: 2.395

3. The cat hemoglobin polymorphism: Southern blot analysis of the beta-globin gene region from cats of various Hb A/Hb B phenotypes.

Authors: J Kasten-Jolly; E C Abraham
Journal: Biochem Genet Date: 1988-04 Impact factor: 1.890

Ruminant globin gene structures suggest an evolutionary role for Alu-type repeats.

1. A comparison of amino acid sequences in the beta-chains of adult bovine hemoglobins A and B.

2. Amino acid sequences in the -chains of adult bovine hemoglobins C-Rhodesia and D-Zambia.

3. Embryonic and fetal hemoglobin in animals.

4. The in vivo production of hemoglobin C in ruminants.

5. The synthesis of haemoglobins A and F in the calf.

6. The formation of foetal and adult haemoglobin in cell cultures of neonatal calf marrow.

7. Molecular evolution of myoglobin and the fossil record: a phylogenetic synthesis.

8. The amino acid sequence of the gamma chain of bovine fetal hemoglobin.

9. Recombination and balanced chromosome polymorphism suggested by DNA sequences 5' to the human delta-globin gene.

10. Gene conversion of deletions in the his4 region of yeast.

1. Remarkably high rate of molecular evolution of ruminant placental lactogens.

2. DNA sequence of a class I pseudogene from the Tla region of the murine MHC: recombination at a B2 alu repetitive sequence.

3. The cat hemoglobin polymorphism: Southern blot analysis of the beta-globin gene region from cats of various Hb A/Hb B phenotypes.

4. A composite transposon 3' to the cow fetal globin gene binds a sequence specific factor.

5. Conservation and variation in the large scale organisation of the globin gene domains of duck and chicken.

6. Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family.

7. High-frequency germ line gene conversion in transgenic mice.

8. Characterization of the cow stomach lysozyme genes: repetitive DNA and concerted evolution.

9. Gene conversion between unlinked sequences in the germline of mice.

10. Rate constancy of globin gene evolution in placental mammals.