Literature DB >> 7007174

Fat inhibition of gastric acid secretion in duodenal ulcer patients before and after proximal gastric vagotomy.

B Kihl, L Olbe.   

Abstract

In seven duodenal ulcer patients the effect of intraduodenal infusion of 20 ml oleic acid on submaximal gastric acid secretion stimulation by a continuous pentagastrin infusion was evaluated before and after proximal gastric vagotomy. In the control tests 20 ml of saline was given. Before vagotomy, oleic acid evoked a significant inhibition of gastric acid secretion of 25% compared with the controls. This inhibition was abolished after proximal gastric vagotomy. The difference in inhibition before and after vagotomy was significant (P=0.01). It is concluded that the vagus nerve in man plays a decisive role in duodenal fat inhibition of gastric acid secretion.

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Year:  1980        PMID： 7007174      PMCID： PMC1419412          DOI： 10.1136/gut.21.12.1056

Source DB:  PubMed          Journal:  Gut        ISSN： 0017-5749            Impact factor:   23.059


  15 in total

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Authors:  K G Wormsley
Journal:  Gut       Date:  1974-01       Impact factor: 23.059

2.  Disturbances in fat digestion induced by acidic jejunal pH due to gastric hypersecretion in man.

Authors:  V L Go; J R Poley; A F Hofmann; W H Summerskill
Journal:  Gastroenterology       Date:  1970-05       Impact factor: 22.682

3.  Candidate hormones of the gut. I. Introduction.

Authors:  M I Grossman
Journal:  Gastroenterology       Date:  1974-10       Impact factor: 22.682

4.  The effect of vagotomy on the inhibition of gastric secretion by intraduodenal fat.

Authors:  A S Ward
Journal:  Br J Surg       Date:  1973-07       Impact factor: 6.939

5.  The effect of fat in the duodenum on gastric secretion before and after truncal vagotomy (T.V.) and highly selective vagotomy (H.S.V.) in man.

Authors:  P J Lyndon; D Jonston
Journal:  Br J Surg       Date:  1972-11       Impact factor: 6.939

6.  Effect of fat in the duodenum on gastric acid secretion before and after vagotomy in man.

Authors:  D Johnston; H L Duthie
Journal:  Scand J Gastroenterol       Date:  1969       Impact factor: 2.423

7.  Effect of perfusion of intestinal loops with acid, fat, or dextrose on gastric secretion.

Authors:  S Konturek; M I Grossman
Journal:  Gastroenterology       Date:  1965-11       Impact factor: 22.682

8.  Inhibition of exogenous gastrin-stimulated gastric secretion by fat in the duodenum.

Authors:  D D Bibler; H N Harkins; L M Nyhus
Journal:  Rev Surg       Date:  1965 Nov-Dec

9.  Fat induced jejunal inhibition of gastric acid secretion in duodenal ulcer patients before and after truncal vagotomy.

Authors:  J Christiansen
Journal:  Ann Surg       Date:  1977-11       Impact factor: 12.969

10.  Effect of vagotomy on the gastric secretory response to intraduodenal osmotic agents in man.

Authors:  A S Ward
Journal:  Gut       Date:  1976-01       Impact factor: 23.059
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  3 in total

1.  Enterogastrone-like effect of peptide YY is vagally mediated in the dog.

Authors:  T N Pappas; H T Debas; I L Taylor
Journal:  J Clin Invest       Date:  1986-01       Impact factor: 14.808

2.  Neurotensin induced inhibition of gastric acid secretion in duodenal ulcer patients before and after parietal cell vagotomy.

Authors:  P S Olsen; J H Pedersen; P Kirkegaard; H Been; F Stadil; J Fahrenkrug; J Christiansen
Journal:  Gut       Date:  1984-05       Impact factor: 23.059

3.  [Neurotensin--what is known about its role as a hormone in the gastrointestinal tract?].

Authors:  V E Eysselein
Journal:  Klin Wochenschr       Date:  1984-06-01
  3 in total

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