Literature DB >> 7003833

IgM antibody to filarial antigens in human cord blood: possibility of transplacental infection.

S Dissanayake, L V de Silva, M M Ismail.   

Abstract

In a hospital in Sri Lanka, antifilarial antibody in maternal and umbilical cord blood was determined by indirect immunofluorescence, enzyme-linked immunosorbent assay and radio-immunoassay. Anti-filarial antibody was detected in 18 of 340 cord blood samples. Specific IgM antibody was detected in 12 cord blood samples. The foetal IgM antibody was probably in response to a transplacental transfer of filarial antigens. The exposure of the foetus to filarial antigens might be beneficial, increasing resistance to infection, or detrimental by inducing at least partial tolerance.

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Year:  1980        PMID： 7003833     DOI： 10.1016/0035-9203(80)90075-9

Source DB:  PubMed          Journal:  Trans R Soc Trop Med Hyg        ISSN： 0035-9203            Impact factor:   2.184


  7 in total

1.  Congenital filarial lymphoedema.

Authors:  P Chaturvedi; B Advani; A A Khan; B C Harinath; A Gawdi
Journal:  Indian J Pediatr       Date:  1991 May-Jun       Impact factor: 1.967

Review 2.  Sex differentials in susceptibility to lymphatic filariasis and implications for maternal child immunity.

Authors:  L Brabin
Journal:  Epidemiol Infect       Date:  1990-10       Impact factor: 2.451

3.  Antifilarial and anti PPD IgM antibodies in cord blood.

Authors:  C B Sanjeevi; P R Narayanan
Journal:  Indian J Pediatr       Date:  1989 Mar-Apr       Impact factor: 1.967

4.  In utero exposure to Onchocerca volvulus: relationship to subsequent infection intensity and cellular immune responsiveness.

Authors:  L H Elson; A Days; M Calvopiña; W Paredes; E Araujo; R H Guderian; J E Bradley; T B Nutman
Journal:  Infect Immun       Date:  1996-12       Impact factor: 3.441

5.  Parasite-specific anergy in human filariasis. Insights after analysis of parasite antigen-driven lymphokine production.

Authors:  T B Nutman; V Kumaraswami; E A Ottesen
Journal:  J Clin Invest       Date:  1987-05       Impact factor: 14.808

6.  Prenatal allergic sensitization to helminth antigens in offspring of parasite-infected mothers.

Authors:  G J Weil; R Hussain; V Kumaraswami; S P Tripathy; K S Phillips; E A Ottesen
Journal:  J Clin Invest       Date:  1983-05       Impact factor: 14.808

7.  Interferon-γ and Interleukin-10 Responses during Clinical Malaria Episodes in Infants Aged 0-2 Years Prenatally Exposed to Plasmodium falciparum: Tanzanian Birth Cohort.

Authors:  Boniphace Sylvester; Dinah B Gasarasi; Said Aboud; Donath Tarimo; Siriel Masawe; Rose Mpembeni; Göte Swedberg
Journal:  J Trop Med       Date:  2018-07-30
  7 in total

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