Literature DB >> 2807447

Antifilarial and anti PPD IgM antibodies in cord blood.

C B Sanjeevi, P R Narayanan.   

Abstract

Tuberculosis and Filariasis are commonly encountered in South India, more so in the low socio-economic group. This study was undertaken to find out the fetal immune response to maternal filariasis and tuberculosis. The presence of anti-filarial and anti-PPD IgG and IgM antibodies in the mother and cord blood at the time of delivery was identified by ELISA. Six out of 29 cases showed IgM against Brugia malayi antigen in the cord blood. In both instances, 6 out of 29 for PPD and 7 out of 29 for B. malayi, the maternal blood too showed the presence of IgM to these two antigens. Comparison with anti-Ascaris lumbricoides IgM antibodies in mother and cord blood in these (6 out of 29 against PPD and 7 out of 29 against B. malayi) cases did not show a similar distribution of IgM antibodies in mother and cord blood, indicating that there is a fetal response to maternal filariasis and tuberculosis.

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Year:  1989        PMID： 2807447     DOI： 10.1007/bf02726609

Source DB:  PubMed          Journal:  Indian J Pediatr        ISSN： 0019-5456            Impact factor:   1.967


  6 in total

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Authors:  E R Stiehm; A J Ammann; J D Cherry
Journal:  N Engl J Med       Date:  1966-11-03       Impact factor: 91.245

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Authors:  S Dissanayake; L V de Silva; M M Ismail
Journal:  Trans R Soc Trop Med Hyg       Date:  1980       Impact factor: 2.184

3.  Helminths and the transmammary route of infection.

Authors:  G C Miller
Journal:  Parasitology       Date:  1981-04       Impact factor: 3.234

4.  Elevation of cord over maternal IgG immunoglobulin: evidence for an active placental IgG transport.

Authors:  P F Kohler; R S Farr
Journal:  Nature       Date:  1966-06-04       Impact factor: 49.962

5.  Effect of mode of delivery on immunoglobulin G concentration in the newborn.

Authors:  W R Jones; R B Payne
Journal:  Am J Obstet Gynecol       Date:  1967-12-15       Impact factor: 8.661

6.  Prenatal allergic sensitization to helminth antigens in offspring of parasite-infected mothers.

Authors:  G J Weil; R Hussain; V Kumaraswami; S P Tripathy; K S Phillips; E A Ottesen
Journal:  J Clin Invest       Date:  1983-05       Impact factor: 14.808
  6 in total
  3 in total

1.  Immunologic tolerance in lymphatic filariasis. Diminished parasite-specific T and B lymphocyte precursor frequency in the microfilaremic state.

Authors:  C L King; V Kumaraswami; R W Poindexter; S Kumari; K Jayaraman; D W Alling; E A Ottesen; T B Nutman
Journal:  J Clin Invest       Date:  1992-05       Impact factor: 14.808

2.  In utero exposure to Onchocerca volvulus: relationship to subsequent infection intensity and cellular immune responsiveness.

Authors:  L H Elson; A Days; M Calvopiña; W Paredes; E Araujo; R H Guderian; J E Bradley; T B Nutman
Journal:  Infect Immun       Date:  1996-12       Impact factor: 3.441

3.  Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset.

Authors:  C L King; S Mahanty; V Kumaraswami; J S Abrams; J Regunathan; K Jayaraman; E A Ottesen; T B Nutman
Journal:  J Clin Invest       Date:  1993-10       Impact factor: 14.808
  3 in total

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