Literature DB >> 700027

The effect of urethane and pentobarbital anaesthesia and hepatic portal vein catheterization on liver blood flow in the rat.

C R Hiley, M S Yates, D J Back.   

Abstract

The effect of urethane and pentobarbital anaesthesia and hepatic portal vein catheterization on liver blood flow was investigated in the rat. Liver blood flow with pentobarbital anaesthesia was 40% greater than with urethane. Hepatic portal vein catheterization had no effect under pentobarbital anaesthesia whereas it produced an 18% fall in liver blood flow with urethane.

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Year:  1978        PMID: 700027     DOI: 10.1007/bf01915348

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  11 in total

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Authors:  G R Wilkinson
Journal:  Annu Rev Pharmacol       Date:  1975       Impact factor: 13.820

2.  Commentary: a physiological approach to hepatic drug clearance.

Authors:  G R Wilkinson; D G Shand
Journal:  Clin Pharmacol Ther       Date:  1975-10       Impact factor: 6.875

3.  120-DAY STUDY OF CARDIAC OUTPUT IN UNANESTHETIZED RATS.

Authors:  V P POPOVIC; K M KENT
Journal:  Am J Physiol       Date:  1964-10

4.  URETHANE ANESTHESIA AND PITUITARY-ADRENAL FUNCTION IN THE RAT.

Authors:  T L SPRIGGS; M A STOCKHAM
Journal:  J Pharm Pharmacol       Date:  1964-09       Impact factor: 3.765

5.  Simultaneous measurement of cardiac output and its distribution with microspheres in the rat.

Authors:  D G McDevitt; A S Nies
Journal:  Cardiovasc Res       Date:  1976-07       Impact factor: 10.787

6.  The pharmacokinetics of norethisterone in the rabbit and rat after systemic and oral administration: effect of phenobarbitone [proceedings].

Authors:  D J Back; A M Breckenridge; F E Gay; P H Rowe; E Smith
Journal:  Br J Pharmacol       Date:  1977-06       Impact factor: 8.739

7.  The effects of four general anaesthetic agents on the regional distribution of cardiac output in the rat [proceedings].

Authors:  G J Bell; C R Hiley; M S Yates
Journal:  Br J Pharmacol       Date:  1977-09       Impact factor: 8.739

8.  Distribution kinetics and intestinal absorption of practolol in the rat.

Authors:  H E Barber; G R Bourne
Journal:  Br J Pharmacol       Date:  1971-03       Impact factor: 8.739

9.  Measurement of the distribution of cardiac output in unanesthetized rats.

Authors:  Y Sasaki; H N Wagner
Journal:  J Appl Physiol       Date:  1971-06       Impact factor: 3.531

10.  The pharmacokinetics of (14C)-edrophonium in normal wistar rats and homozygous Gunn rats with ligated renal pedicles.

Authors:  D J Back; T N Calvey
Journal:  Br J Pharmacol       Date:  1974-05       Impact factor: 8.739

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  5 in total

1.  The effect of a single treatment with cigarette smoke on the blood levels and hemodynamic effects of propranolol in rats.

Authors:  T Berkan; L Ustünes; Z Kerry; M Karol; M Tosun; C Yalçinkaya; A Ozer
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1989 Jul-Sep       Impact factor: 2.441

2.  Excessive bleeding at hepatic resection after experimental liver denervation.

Authors:  C M Kullendorff; E Zoucas; J Lindfeldt; T Holmin
Journal:  World J Surg       Date:  1984-02       Impact factor: 3.352

3.  First pass effect of pinazepam in the rabbit liver.

Authors:  G M Pacifici; G F Placidi
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1982       Impact factor: 2.441

4.  Method to estimate the rate and extent of intestinal absorption in conscious rats using an absorption probe and portal blood sampling.

Authors:  D J Hoffman; T Seifert; A Borre; H N Nellans
Journal:  Pharm Res       Date:  1995-06       Impact factor: 4.200

5.  Measurement of total liver blood flow in intact anesthetized rats using ultrasound imaging.

Authors:  Christopher R Gibson; Alexa Gleason; Eric Messina
Journal:  Pharmacol Res Perspect       Date:  2021-04
  5 in total

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