Literature DB >> 6998719

Inhibitors of the acrosomal proteinase acrosin: human urinary trypsin inhibitor (UTI) and 4-(2-carboxyethyl) phenyl trans 4-aminomethylcyclohexanecarboxylate hydrochloride (DV-1006).

H Sumi, N Toki.   

Abstract

Human urinary trypsin inhibitor (UTI) and (4-(2-carboxyethyl) phenyl trans 4-aminoethylcyclohexanecarboxylate hydrochloride (DV-1006) competitively inhibited the human acrosomal proteinase acrosin; Ki values were 1.2 x 10-8 M and 9.4 x 10-7, respectively.

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Year:  1980        PMID： 6998719     DOI： 10.1007/bf01965994

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  6 in total

1.  The determination of enzyme inhibitor constants.

Authors:  M DIXON
Journal:  Biochem J       Date:  1953-08       Impact factor: 3.857

2.  Inhibitory effects of -amino acid esters on trypsin, plasmin, plasma kallikrein and thrombin.

Authors:  M Muramatu; S Fujii
Journal:  Biochim Biophys Acta       Date:  1971-07-21

3.  Leupeptin and antipain. Strong competitive inhibitors of sperm acrosomal proteinase (boar acrosin) and kallikreins from porcine organs (pancreas, submand. glands, urine).

Authors:  H Fritz; B Förg-Brey; H Umezawa
Journal:  Hoppe Seylers Z Physiol Chem       Date:  1973 Oct-Nov

4.  [Trypsin inhibitors in human urine (author's transl)].

Authors:  H Sumi; K Minakata; Y Takada; A Takada
Journal:  Nihon Seirigaku Zasshi       Date:  1977-03

5.  Studies on human urinary trypsin inhibitor. 1. Its modification on treatment of urine with acid.

Authors:  H Sumi; Y Takada; A Takada
Journal:  Thromb Res       Date:  1977-12       Impact factor: 3.944

6.  Acrosomal proteinase and proteinase inhibitor of human spermatozoa.

Authors:  L J Zaneveld; B M Dragoje; G F Schumacher
Journal:  Science       Date:  1972-08-25       Impact factor: 47.728
  6 in total

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