Literature DB >> 6998711

Inactivation of yeast glucose-6-P dehydrogenase by aspirin.

P F Han, G Y Han, H C McBay, J Johnson.   

Abstract

Glucose-6-P dehydrogenase is irreversibly inactivated by treatment with Na salts of aspirin. Kinetic data show that 1 molecule of aspirin reacts with each active unit when the enzyme is inactivated. The rate of inactivation is enhanced with increasing pH but is reduced in the presence of glucose-6-P or NADP+. Na salicylate fails to inactivate the enzyme.

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Year:  1980        PMID： 6998711     DOI： 10.1007/bf01976092

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  11 in total

1.  INACTIVATION OF MYOSIN BY 2,4-DINITROPHENOL AND PROTECTION BY ADENOSINE TRIPHOSPHATE AND OTHER PHOSPHATE COMPOUNDS.

Authors:  H M LEVY; P D LEBER; E M RYAN
Journal:  J Biol Chem       Date:  1963-11       Impact factor: 5.157

2.  Alteration of the regulatory properties of chicken liver fructose-1,6-bisphosphatase by treatment with aspirin.

Authors:  P F Han; G Y Han; H C McBay; J Johnson
Journal:  Biochem Biophys Res Commun       Date:  1978-11-29       Impact factor: 3.575

3.  Evidence for an essential lysine in glucose-6-phosphate dehydrogenase from Leuconostoc mesenteroides.

Authors:  M Milhausen; H R Levy
Journal:  Eur J Biochem       Date:  1975-01-02

4.  Modification of fructose-1,6-diphosphatase with pyridoxal 5'-phosphate. Evidence for the participation of lysyl residues at the active site.

Authors:  G Colombo; F Marcus
Journal:  Biochemistry       Date:  1974-07-16       Impact factor: 3.162

5.  Selective alteration of the regulatory properties of fructose 1,6-diphosphatase by modification with pyridoxal 5'-phosphate.

Authors:  G Colombo; E Hubert; F Marcus
Journal:  Biochemistry       Date:  1972-05-09       Impact factor: 3.162

6.  In vitro acetylation of plasma proteins, enzymes and DNA by aspirin.

Authors:  R N Pinckard; D Hawkins; R S Farr
Journal:  Nature       Date:  1968-07-06       Impact factor: 49.962

7.  Essential arginyl residues in mitochondrial adenosine triphosphatase.

Authors:  F Marcus; S M Schuster; H A Lardy
Journal:  J Biol Chem       Date:  1976-03-25       Impact factor: 5.157

8.  Sites of acetylation of sickle cell hemoglobin by aspirin.

Authors:  M Shamsuddin; R G Mason; J M Ritchey; G R Honig; I M Klotz
Journal:  Proc Natl Acad Sci U S A       Date:  1974-12       Impact factor: 11.205

9.  Acetylation of the NH2-terminal serine of prostaglandin synthetase by aspirin.

Authors:  G J Roth; C J Siok
Journal:  J Biol Chem       Date:  1978-06-10       Impact factor: 5.157

10.  Structural changes in human serum albumin induced by ingestion of acetylsalicylic acid.

Authors:  D Hawkins; R N Pinckard; I P Crawford; R S Farr
Journal:  J Clin Invest       Date:  1969-03       Impact factor: 14.808
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  2 in total

1.  Kinetics of protein modification and enzyme inactivation reactions: interpretation of reaction order.

Authors:  E T Rakitzis
Journal:  Biochem J       Date:  1985-10-15       Impact factor: 3.857

2.  Irreversible inactivation of yeast glucose-6-P dehydrogenase by penicillin G.

Authors:  P F Han; Y H Mariam; S H Pollock; H W Matthews; J Johnson
Journal:  Experientia       Date:  1981-07-15
  2 in total

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