Literature DB >> 6995339

Identification of a cytotoxin produced by Legionella pneumophila.

R L Friedman, B H Iglewski, R D Miller.   

Abstract

Culture filtrates of Legionella pneumophila were cytotoxic for Chinese hamster ovary cells. The cytotoxin was found to be methanol soluble, heat stable, and stable from pH 5 through 8.

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Year:  1980        PMID： 6995339      PMCID： PMC551106          DOI： 10.1128/iai.29.1.271-274.1980

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  11 in total

1.  Toxin inhibitors of protein synthesis: production, purification, and assay of Pseudomonas aeruginosa toxin A.

Authors:  B H Iglewski; J C Sadoff
Journal:  Methods Enzymol       Date:  1979       Impact factor: 1.600

2.  The pathology of Legionnaires' disease. Fourteen fatal cases from the 1977 outbreak in Vermont.

Authors:  W C Winn; F L Glavin; D P Perl; J L Keller; T L Andres; T M Brown; C M Coffin; J E Sensecqua; L N Roman; J E Craighead
Journal:  Arch Pathol Lab Med       Date:  1978-07       Impact factor: 5.534

3.  Legionnaires' disease in non-Legionnaires. A report of five cases.

Authors:  H M Friedman
Journal:  Ann Intern Med       Date:  1978-03       Impact factor: 25.391

4.  Demonstration of the agent of Legionnaires' disease in tissue.

Authors:  F W Chandler; M D Hicklin; J A Blackmon
Journal:  N Engl J Med       Date:  1977-12-01       Impact factor: 91.245

5.  Legionnaires' disease. Pathological and historical aspects of a 'new' disease.

Authors:  J A Blackmon; M D Hicklin; F W Chandler
Journal:  Arch Pathol Lab Med       Date:  1978-07       Impact factor: 5.534

6.  Exotoxin activity associated with the Legionnaires disease bacterium.

Authors:  W B Baine; J K Rasheed; D C Mackel; C A Bopp; J G Wells; A F Kaufmann
Journal:  J Clin Microbiol       Date:  1979-03       Impact factor: 5.948

7.  Legionnaires' disease: description of an epidemic of pneumonia.

Authors:  D W Fraser; T R Tsai; W Orenstein; W E Parkin; H J Beecham; R G Sharrar; J Harris; G F Mallison; S M Martin; J E McDade; C C Shepard; P S Brachman
Journal:  N Engl J Med       Date:  1977-12-01       Impact factor: 91.245

8.  Legionnaires' disease: isolation of a bacterium and demonstration of its role in other respiratory disease.

Authors:  J E McDade; C C Shepard; D W Fraser; T R Tsai; M A Redus; W R Dowdle
Journal:  N Engl J Med       Date:  1977-12-01       Impact factor: 91.245

9.  "Endotoxicity" of the Legionnaires' disease bacterium.

Authors:  K H Wong; C W Moss; D H Hochstein; R J Arko; W O Schalla
Journal:  Ann Intern Med       Date:  1979-04       Impact factor: 25.391

10.  Growth of Legionnaires disease bacterium (Legionella pneumophila) in chemically defined medium.

Authors:  W J Warren; R D Miller
Journal:  J Clin Microbiol       Date:  1979-07       Impact factor: 5.948
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  27 in total

Review 1.  Virulence factors of the family Legionellaceae.

Authors:  J N Dowling; A K Saha; R H Glew
Journal:  Microbiol Rev       Date:  1992-03

2.  Legionella pneumophila inhibits protein synthesis in Chinese hamster ovary cells.

Authors:  K T McCusker; B A Braaten; M W Cho; D A Low
Journal:  Infect Immun       Date:  1991-01       Impact factor: 3.441

3.  Early events in phagosome establishment are required for intracellular survival of Legionella pneumophila.

Authors:  L A Wiater; K Dunn; F R Maxfield; H A Shuman
Journal:  Infect Immun       Date:  1998-09       Impact factor: 3.441

4.  Simplified quantitative assay system for measuring activities of drugs against intracellular Legionella pneumophila.

Authors:  F Higa; N Kusano; M Tateyama; T Shinzato; N Arakaki; K Kawakami; A Saito
Journal:  J Clin Microbiol       Date:  1998-05       Impact factor: 5.948

5.  Interactions between Naegleria fowleri and Legionella pneumophila.

Authors:  A L Newsome; R L Baker; R D Miller; R R Arnold
Journal:  Infect Immun       Date:  1985-11       Impact factor: 3.441

6.  Genetic, immunological, and cytotoxic comparisons of Legionella proteolytic activities.

Authors:  F D Quinn; M G Keen; L S Tompkins
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

7.  Lgt: a family of cytotoxic glucosyltransferases produced by Legionella pneumophila.

Authors:  Yury Belyi; Irina Tabakova; Michael Stahl; Klaus Aktories
Journal:  J Bacteriol       Date:  2008-02-15       Impact factor: 3.490

8.  Cloning and characterization of the gene encoding the major cell-associated phospholipase A of Legionella pneumophila, plaB, exhibiting hemolytic activity.

Authors:  Antje Flieger; Kerstin Rydzewski; Sangeeta Banerji; Markus Broich; Klaus Heuner
Journal:  Infect Immun       Date:  2004-05       Impact factor: 3.441

9.  Comparison of guinea pig and protozoan models for determining virulence of Legionella species.

Authors:  B S Fields; J M Barbaree; E B Shotts; J C Feeley; W E Morrill; G N Sanden; M J Dykstra
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441

10.  Fate of Legionella pneumophila Philadelphia-1 strain in resident, elicited, activated, and immune peritoneal macrophages of guinea pigs.

Authors:  S Yoshida; Y Mizuguchi; Y Nikaido; M Mitsuyama; K Nomoto
Journal:  Infect Immun       Date:  1987-10       Impact factor: 3.441
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