Literature DB >> 69939

A new factor that may control collagen resorption.

J J Reynolds, G Murphy, A Sellers, E Cartwright.   

Abstract

Specific collagenases responsible for the initial enzymic step leading to degradation of the collagen fibrils of connective tissues have been found in both latent and active forms. The most important factor controlling the local activity of collagenase extracellularly may be an inhibitor that is synthesised by connective tissues, and it is proposed that latent enzymes are all enzyme-inhibitor complexes.

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Year:  1977        PMID: 69939     DOI: 10.1016/s0140-6736(77)91490-8

Source DB:  PubMed          Journal:  Lancet        ISSN: 0140-6736            Impact factor:   79.321


  16 in total

Review 1.  The role of the macrophage in collagen resorption during chronic inflammation. A new look at an old hypothesis.

Authors:  D A Deporter
Journal:  Agents Actions       Date:  1979-06

2.  Neutral metallo-proteinases of rabbit bone. Separation in latent forms of distinct enzymes that when activated degrade collagen, gelatin and proteoglycans.

Authors:  A Sellers; J J Reynolds; M C Meikle
Journal:  Biochem J       Date:  1978-05-01       Impact factor: 3.857

Review 3.  Lysosomes and the connective tissue diseases.

Authors:  L Bitensky
Journal:  J Clin Pathol Suppl (R Coll Pathol)       Date:  1978

4.  Activation in vitro of rheumatoid synovial collagenase from cell cultures.

Authors:  C A Vater; C L Mainardi; E D Harris
Journal:  J Clin Invest       Date:  1978-11       Impact factor: 14.808

5.  The interaction of purified rabbit bone collagenase with purified rabbit bone metalloproteinase inhibitor.

Authors:  T E Cawston; G Murphy; E Mercer; W A Galloway; B L Hazleman; J J Reynolds
Journal:  Biochem J       Date:  1983-05-01       Impact factor: 3.857

6.  Lymphoedema of the rabbit ear following partial and complete lymphatic blockade; its effects on fibrotic development, enzyme types and their activity levels.

Authors:  N B Piller; L Clodius
Journal:  Br J Exp Pathol       Date:  1978-06

7.  Collagenase and collagenase inhibitor levels following changes in bone resorption in vitro.

Authors:  A Sellers; M C Meikle; J J Reynolds
Journal:  Calcif Tissue Int       Date:  1980       Impact factor: 4.333

8.  The extraction of a neutral metalloproteinase from the involuting rat uterus, and its action on cartilage proteoglycan.

Authors:  A Sellers; J F Woessner
Journal:  Biochem J       Date:  1980-09-01       Impact factor: 3.857

9.  Human mononuclear cell factors mediate cartilage matrix degradation through chondrocyte activation.

Authors:  H E Jasin; J T Dingle
Journal:  J Clin Invest       Date:  1981-09       Impact factor: 14.808

10.  The production in culture of metalloproteinases and an inhibitor by joint tissues from normal rabbits, and from rabbits with a model arthritis. I. Synovium.

Authors:  G J Cambray; G Murphy; D P Page-Thomas; J J Reynolds
Journal:  Rheumatol Int       Date:  1981       Impact factor: 2.631

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