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Literature DB >> 6993772

New placental and pregnancy proteins as possible markers in oncology.

Abstract

A number of placental and pregnancy proteins has been detected by immunochemical methods in extracts from human term placentae. Several of these proteins already have been isolated and characterized and are now investigated for their usefulness as markers in oncology. Several of these proteins so long tested appear to be useful as markers in monitoring tumour patients, i.e. in the early detection of tumour recurrence or metastases and in the control of therapy. In addition, we hope that a combination of several of these new markers with already established tumour markers will enable to better diagnose tumours. Also will the use of solitary tissue proteins aid in the differential diagnosis of cancers.

Entities: Disease Gene Species

Mesh：

Substances：
Pregnancy Proteins

Year: 1980 PMID： 6993772 DOI： 10.1007/bf01477065

Source DB: PubMed Journal: Klin Wochenschr ISSN： 0023-2173

15 in total

1. Pregnancy associated alpha2-glycoprotein in malignant melanoma.

Authors: H W Bauer; K E Deutschmann; H H Peter; H Bohn
Journal: Eur J Cancer Date: 1979-01 Impact factor: 9.162

2. The radioimmunoassay of placental protein 5 and circulating levels in maternal blood in the third trimester of normal pregnancy.

Authors: B Obiekwe; D J Pendlebury; Y B Gordeon; J G Grudzinskas; T Chard; H Bohn
Journal: Clin Chim Acta Date: 1979-08-01 Impact factor: 3.786

6. [Detection and characterization of pregnancy proteins in the human placenta and their quantitative immunochemical determination in sera from pregnant women].

Authors: H Bohn
Journal: Arch Gynakol Date: 1971-10-28

7. Serum concentrations of SP1 (pregnancy-specific-beta1-glycoprotein) in healthy, nonpregnant individuals, and in patients with nontrophoblastic malignant neoplasms.

Authors: H Würz
Journal: Arch Gynecol Date: 1979-03-28

8. Correlation of the blood-level of a pregnancy-associated alpha-macroglobulin with the clinical course of cancer patients.

Authors: W H Stimson
Journal: Lancet Date: 1975-04-05 Impact factor: 79.321

9. Development of radioimmunoassay for pregnancy-specific beta1-globulin and its measurement in serum of patients with trophoblastic and non-trophoblastic tumours.

Authors: Y S Tatarinov; A V Sokolov
Journal: Int J Cancer Date: 1977-02-15 Impact factor: 7.396

10. [Correlation of alpha-2 pregnancy associated glycoprotein with the clinical course of bronchial carcinoma (author's transl)].

Authors: H W Bauer; C Gropp; A Sieber; H Bohn
Journal: Thoraxchir Vask Chir Date: 1977-06

4 in total

1. Immunohistochemical location of placental proteins (PP8, 9, 10, 11, 12) in human term placentae.

Authors: N Inaba; T Renk; H Bohn
Journal: Arch Gynecol Date: 1980

2. Enzyme immunoassay for placental protein 4 (PP4) and its possible diagnostic significance in patients with genital tract cancer.

Authors: Y Ota; N Inaba; S Shirotake; I Fukazawa; H Takamizawa; H Bohn
Journal: Arch Gynecol Obstet Date: 1990 Impact factor: 2.344

3. Immunohistochemical detection of pregnancy and placental proteins in human and cynomolgus monkey (Macaca Fascicularis) peripheral blood cells.

Authors: N Inaba; T Renk; W Ax; E Weinmann; S Schottler; H Bohn
Journal: Blut Date: 1981-11

4. Ectopic production of placenta-"specific" tissue proteins (PP5 and PP11) by malignant breast tumors.

Authors: N Inaba; T Renk; E Daume; H Bohn
Journal: Arch Gynecol Date: 1981