Literature DB >> 699188

Rat liver microsome-mediated binding to DNA of 3-amino-1-methyl-5H-pyrido[4,3-b]indole, a potent mutagen isolated from tryptophan pyrolysate.

Y Hashimoto, K Takeda, K Shudo, T Okamoto, T Sugimura, T Kosuge.   

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Year:  1978        PMID： 699188     DOI： 10.1016/0009-2797(78)90047-9

Source DB:  PubMed          Journal:  Chem Biol Interact        ISSN： 0009-2797            Impact factor:   5.192


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  4 in total

1.  There is a correlation between the DNA affinity and mutagenicity of several 3-amino-1-methyl-5H-pyrido[4,3-b]indoles.

Authors:  J M Pezzuto; P P Lau; Y Luh; P D Moore; G N Wogan; S M Hecht
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

2.  Quantitative predictability of carcinogenicity of the covalent binding index of chemicals to DNA: comparison of the in vivo and in vitro assays.

Authors:  M Taningher; G Saccomanno; L Santi; S Grilli; S Parodi
Journal:  Environ Health Perspect       Date:  1990-03       Impact factor: 9.031

Review 3.  A current genotoxicity database for heterocyclic thermic food mutagens. I. Genetically relevant endpoints.

Authors:  F T Hatch
Journal:  Environ Health Perspect       Date:  1986-08       Impact factor: 9.031

4.  Chemical modification of DNA with muta-carcinogens. I. 3-Amino-1-methyl-5H-pyrido[4,3-b]indole and 2-amino-6-methyldipyrido[1,2-a:3',2'-d]imidazole: metabolic activation and structure of the DNA adducts.

Authors:  Y Hashimoto; K Shudo
Journal:  Environ Health Perspect       Date:  1985-10       Impact factor: 9.031
  4 in total

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