Literature DB >> 6982728

Inhibitory effects of bilirubin and photobilirubin on neonatal and adult T lymphocytes and granulocytes.

F F Rubaltelli, B Granati, A Fortunato, A Piovesan, G Casara, P Colleselli, G Semenzato.   

Abstract

The lymphoproliferative response to phytohemagglutinin of lymphocytes and spontaneous motility, chemotaxis and phagocytic activity of granulocytes were studied in the newborn and adult blood in the presence of bilirubin and photobilirubin. All of these activities were inhibited to the same extent by these substances. In addition, a significant difference between newborn and adult values was found. In conclusion, the authors suggest that phototherapy does not decrease bilirubin cellular toxicity.

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Year:  1982        PMID： 6982728     DOI： 10.1159/000241589

Source DB:  PubMed          Journal:  Biol Neonate        ISSN： 0006-3126


  8 in total

1.  Impaired nonspecific cellular immunity in experimental cholestasis.

Authors:  P T Roughneen; D B Drath; A D Kulkarni; B J Rowlands
Journal:  Ann Surg       Date:  1987-11       Impact factor: 12.969

Review 2.  The immunosuppressive effects of bilirubin.

Authors:  V Vĕtvicka; P Síma; I Miler; M Bilej
Journal:  Folia Microbiol (Praha)       Date:  1991       Impact factor: 2.099

3.  The stimulatory effect of bilirubin on phagocytic activity.

Authors:  M Bilej; V Vĕtvicka; P Síma
Journal:  Folia Microbiol (Praha)       Date:  1989       Impact factor: 2.099

4.  T-lymphocyte transformation in experimental obstructive jaundice: the role of serum-suppressive factors.

Authors:  R L Thompson; S Ranjbar; B J Rowlands
Journal:  World J Surg       Date:  1993 Nov-Dec       Impact factor: 3.352

5.  The in vitro cytotoxic effect of bilirubin on human lymphocytes and granulocytes.

Authors:  I Miler; M Indrová; J Bubeník; J Vondrácek
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099

6.  The effect of bilirubin on the Fc receptor expression and phagocytic activity of mouse peritoneal macrophages.

Authors:  V Vĕtvicka; I Miler; P Síma; L Táborský; L Fornůsek
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099

Review 7.  Management of neonatal hyperbilirubinaemia and prevention of kernicterus.

Authors:  F F Rubaltelli; P F Griffith
Journal:  Drugs       Date:  1992-06       Impact factor: 9.546

8.  The effect of bilirubin on the phagocytic activity of mouse peripheral granulocytes and monocytes in vivo.

Authors:  I Miler; V Vĕtvicka; P Síma; L Táborský
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099
  8 in total

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