Literature DB >> 6982027

Enteropathy complicating maintenance therapy in acute lymphoblastic leukaemia.

I J Lewis, D Mainwaring, J Martin.   

Abstract

Seven patients being treated for acute lymphoblastic leukaemia between March 1976 and March 1981, in accordance with Medical Research Council protocols, developed clinical malabsorption while on maintenance chemotherapy. All of them received weekly methotrexate and 6 of the 7 were given co-trimoxazole. Five patients had folate deficiency. Stopping the anti-leukaemic therapy led to a resolution of gastrointestinal symptoms. A combined effect of methotrexate and co-trimoxazole is postulated.

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Year:  1982        PMID： 6982027      PMCID： PMC1627776          DOI： 10.1136/adc.57.9.663

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN： 0003-9888            Impact factor:   3.791


  14 in total

1.  Use of combinations of trimethoprim and sulphamethoxazole in the treatment of chest infections.

Authors:  D T Hughes
Journal:  Med J Aust       Date:  1973-06-30       Impact factor: 7.738

2.  Species differences among dihydrofolate reductases as a basis for chemotherapy.

Authors:  G H Hitchings
Journal:  Postgrad Med J       Date:  1969-11       Impact factor: 2.401

3.  Five-year follow-up of "total therapy" of childhood lymphocytic leukemia.

Authors:  D Pinkel
Journal:  JAMA       Date:  1971-04-26       Impact factor: 56.272

4.  One-hour blood-xylose screening-test for coeliac disease in infants and young children.

Authors:  C J Rolles; S Nutter; M J Kendall; C M Anderson
Journal:  Lancet       Date:  1973-11-10       Impact factor: 79.321

5.  Toxicity of trimethoprim-sulphamethoxazole in patients with megaloblastic haemopoiesis.

Authors:  I Chanarin; J M England
Journal:  Br Med J       Date:  1972-03-11

6.  Methotrexate-induced malabsorption in children with acute lymphoblastic leukaemia.

Authors:  A W Craft; H Kay; D N Lawson; T J McElwain
Journal:  Br Med J       Date:  1977-12-10

7.  Successful chemoprophylaxis for Pneumocystis carinii pneumonitis.

Authors:  W T Hughes; S Kuhn; S Chaudhary; S Feldman; M Verzosa; R J Aur; C Pratt; S L George
Journal:  N Engl J Med       Date:  1977-12-29       Impact factor: 91.245

8.  Acute pancytopenia due to megaloblastic arrest in association with co-trimoxazole.

Authors:  E A Blackwell; G A Hawson; J Leer; B Bain
Journal:  Med J Aust       Date:  1978-07-01       Impact factor: 7.738

9.  Growth hormone deficiency after treatment of acute leukaemia in children.

Authors:  S M Shalet; C G Beardwell; P H Jones; D Pearson
Journal:  Arch Dis Child       Date:  1976-07       Impact factor: 3.791

10.  Structural and functional abnormalities of the small intestine due to nutritional folic acid deficiency in infancy.

Authors:  G P Davidson; R R Townley
Journal:  J Pediatr       Date:  1977-04       Impact factor: 4.406
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  9 in total

1.  Intestinal permeability during chemotherapy for childhood tumours.

Authors:  J V Pledger; A D Pearson; A W Craft; M F Laker; E J Eastham
Journal:  Eur J Pediatr       Date:  1988-02       Impact factor: 3.183

2.  Development of Bullous Acrodermatitis Enteropathica during the Course of Chemotherapy for Acute Lymphocytic Leukemia.

Authors:  Ji Hoon Chun; Ji Hye Baek; Nak Gyun Chung; Jung Eun Kim; Baik Kee Cho; Hyun Jeong Park
Journal:  Ann Dermatol       Date:  2011-12-27       Impact factor: 1.444

3.  Topical methotrexate alters solute and water transport in the rat jejunum in vivo and rabbit ileum in vitro.

Authors:  C R Pinkerton; I W Booth; P J Milla
Journal:  Gut       Date:  1985-07       Impact factor: 23.059

4.  Acute lymphoblastic leukaemia: trimethoprim resistant organisms during treatment.

Authors:  H P McDowell; P Shears; C A Hart; J Martin
Journal:  Arch Dis Child       Date:  1987-06       Impact factor: 3.791

5.  Weight gain and height velocity during prolonged first remission from acute lymphoblastic leukaemia.

Authors:  C P Sainsbury; R G Newcombe; I A Hughes
Journal:  Arch Dis Child       Date:  1985-09       Impact factor: 3.791

6.  Disturbance of 6-mercaptopurine metabolism by cotrimoxazole in childhood lymphoblastic leukaemia.

Authors:  C A Rees; L Lennard; J S Lilleyman; J L Maddocks
Journal:  Cancer Chemother Pharmacol       Date:  1984       Impact factor: 3.333

7.  Red blood cell methotrexate and folate levels in children with acute lymphoblastic leukemia undergoing therapy: a Pediatric Oncology Group pilot study.

Authors:  M L Graham; J J Shuster; B A Kamen; D L Cheo; M P Harrison; B G Leventhal; D J Pullen; V M Whitehead
Journal:  Cancer Chemother Pharmacol       Date:  1992       Impact factor: 3.333

8.  Functional and structural changes of the human proximal small intestine after cytotoxic therapy.

Authors:  D Cunningham; R J Morgan; P R Mills; L M Nelson; P G Toner; M Soukop; C S McArdle; R I Russell
Journal:  J Clin Pathol       Date:  1985-03       Impact factor: 3.411

9.  Methotrexate enterotoxicity: influence of drug dose and timing in the rat.

Authors:  C R Pinkerton; P J Milla
Journal:  Br J Cancer       Date:  1984-01       Impact factor: 7.640
  9 in total

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