Literature DB >> 3130249

Intestinal permeability during chemotherapy for childhood tumours.

J V Pledger1, A D Pearson, A W Craft, M F Laker, E J Eastham.   

Abstract

The intestinal permeability to mannitol and lactulose was measured in 29 children receiving treatment for solid tumours. At the time of study they had no gastrointestinal symptoms and appeared clinically well. However, there was a significant reduction in the absorption of mannitol when compared to normal children. This small bowel dysfunction may result in malabsorption of nutrients and drugs. There was a significant correlation between decreased mannitol absorption and low nutritional status.

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Year:  1988        PMID: 3130249     DOI: 10.1007/bf00442208

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN: 0340-6199            Impact factor:   3.183


  24 in total

1.  Estimation of disaccharides in plasma and urine by gas-liquid chromatography.

Authors:  M F Laker
Journal:  J Chromatogr       Date:  1979-05-01

2.  Use of decline in D-xylose absorption to predict infection following intensive chemotherapy.

Authors:  D A Pegues; K M Daly; R A Larson
Journal:  Cancer Treat Rep       Date:  1984-12

3.  Small bowel enterocyte abnormalities caused by methotrexate treatment in acute lymphoblastic leukaemia of childhood.

Authors:  N J Gwavava; C R Pinkerton; J F Glasgow; J M Sloan; J M Bridges
Journal:  J Clin Pathol       Date:  1981-07       Impact factor: 3.411

4.  Classification and definition of protein-calorie malnutrition.

Authors:  J C Waterlow
Journal:  Br Med J       Date:  1972-09-02

5.  The effect of oral methotrexate on the rat intestine.

Authors:  J W Robinson; J A Antonioli; A Vannotti
Journal:  Biochem Pharmacol       Date:  1966-10       Impact factor: 5.858

6.  Mannitol estimation in biological fluids by gas-liquid chromatography of trimethylsilyl derivatives.

Authors:  M F Laker; J N Mount
Journal:  Clin Chem       Date:  1980-03       Impact factor: 8.327

7.  Evaluation of mannitol for use as a probe marker of gastrointestinal permeability in man.

Authors:  M F Laker; H J Bull; I S Menzies
Journal:  Eur J Clin Invest       Date:  1982-12       Impact factor: 4.686

8.  Intestinal permeability changes and excretion of micro-organisms in stools of infants with diarrhoea and vomiting.

Authors:  L T Weaver; P D Chapman; C R Madeley; M F Laker; R Nelson
Journal:  Arch Dis Child       Date:  1985-04       Impact factor: 3.791

9.  Methotrexate-induced malabsorption in children with acute lymphoblastic leukaemia.

Authors:  A W Craft; H Kay; D N Lawson; T J McElwain
Journal:  Br Med J       Date:  1977-12-10

10.  Standard of weight-for-height for English children from age 5.0 to 11.0 years.

Authors:  S Chinn; R W Morris
Journal:  Ann Hum Biol       Date:  1980 Sep-Oct       Impact factor: 1.533

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  2 in total

Review 1.  Intestinal permeability.

Authors:  I Bjarnason
Journal:  Gut       Date:  1994-01       Impact factor: 23.059

2.  Intestinal barrier function and secretion in methotrexate-induced rat intestinal mucositis.

Authors:  B A Carneiro-Filho; I P F Lima; D H Araujo; M C Cavalcante; G H P Carvalho; G A C Brito; V Lima; S M N Monteiro; F N Santos; R A Ribeiro; A A M Lima
Journal:  Dig Dis Sci       Date:  2004-01       Impact factor: 3.199

  2 in total

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