Literature DB >> 6981160

Adverse reactions to trimethoprim-sulfamethoxazole in hospitalized patients.

H Jick.   

Abstract

Of 1,121 hospitalized recipients of trimethoprim-sulfamethoxazole, 91 (8%) experienced reactions that were attributed to this drug. The most common adverse effects were gastrointestinal upset (3.9%) and skin reactions (3.3%). Serious toxicity attributable to the drug was rare.

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Year:  1982        PMID: 6981160     DOI: 10.1093/clinids/4.2.426

Source DB:  PubMed          Journal:  Rev Infect Dis        ISSN: 0162-0886


  37 in total

1.  Trimethoprim- sulfamethoxazole: pharmacokinetics, clinical uses, and adverse reactions.

Authors:  M A Kielhofner
Journal:  Tex Heart Inst J       Date:  1990

Review 2.  Considerations when prescribing trimethoprim-sulfamethoxazole.

Authors:  Joanne M-W Ho; David N Juurlink
Journal:  CMAJ       Date:  2011-10-11       Impact factor: 8.262

Review 3.  Idiosyncratic drug reactions: possible role of reactive metabolites generated by leukocytes.

Authors:  J P Uetrecht
Journal:  Pharm Res       Date:  1989-04       Impact factor: 4.200

Review 4.  HIV medicine: drug side effects and interactions.

Authors:  C M Bates
Journal:  Postgrad Med J       Date:  1996-01       Impact factor: 2.401

5.  Thrombophlebitis migrans following co-trimoxazole therapy.

Authors:  J Verne-Pignatelli; G P Spickett; A G Dalgleish; A M Denman
Journal:  Postgrad Med J       Date:  1989-01       Impact factor: 2.401

Review 6.  Trimethoprim-induced hyperkalaemia: clinical data, mechanism, prevention and management.

Authors:  M A Perazella
Journal:  Drug Saf       Date:  2000-03       Impact factor: 5.606

7.  Comparison of dosages, intervals, and drugs in the prevention of Pneumocystis carinii pneumonia.

Authors:  W T Hughes
Journal:  Antimicrob Agents Chemother       Date:  1988-05       Impact factor: 5.191

8.  In vitro cytotoxicity as a marker of hypersensitivity to sulphamethoxazole in patients with HIV.

Authors:  A Carr; B Tindall; R Penny; D A Cooper
Journal:  Clin Exp Immunol       Date:  1993-10       Impact factor: 4.330

Review 9.  Hypersensitivity reactions to non-beta-lactam antibiotics.

Authors:  Stephen A Tilles; Christopher G Slatore
Journal:  Clin Rev Allergy Immunol       Date:  2003-06       Impact factor: 8.667

Review 10.  Pentamidine isethionate. A review of its antiprotozoal activity, pharmacokinetic properties and therapeutic use in Pneumocystis carinii pneumonia.

Authors:  K L Goa; D M Campoli-Richards
Journal:  Drugs       Date:  1987-03       Impact factor: 9.546

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