Literature DB >> 12721393

Hypersensitivity reactions to non-beta-lactam antibiotics.

Stephen A Tilles1, Christopher G Slatore.   

Abstract

As alternatives to beta lactam antibiotics continue to be developed, an increasing number of patients are experiencing hypersensitivity reactions to these agents. Unfortunately, unlike penicillin, there are no validated skin testing reagents to aid in confirming the presence of specific IgE antibodies to these drugs. This review summarizes what is known about hypersensitivity reactions to non-beta lactam antibiotics, and includes practical approaches to readministering these drugs in selected situations. Sulfonamides, vancomycin, macrolides, tetracyclines, fluoroquinolones, and anti-virals are included in the discussion.

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Year:  2003        PMID: 12721393     DOI: 10.1385/CRIAI:24:3:221

Source DB:  PubMed          Journal:  Clin Rev Allergy Immunol        ISSN: 1080-0549            Impact factor:   8.667


  31 in total

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Journal:  Ann Allergy       Date:  1992-04

2.  Rapid oral desensitization for sulfonamides in patients with the acquired immunodeficiency syndrome.

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3.  Fixed drug eruption induced by ofloxacin.

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Journal:  Contact Dermatitis       Date:  1996-06       Impact factor: 6.600

Review 4.  Comparative tolerability of erythromycin and newer macrolide antibacterials in paediatric patients.

Authors:  N Principi; S Esposito
Journal:  Drug Saf       Date:  1999-01       Impact factor: 5.606

Review 5.  Clinical use of the fluoroquinolones.

Authors:  R C Owens; P G Ambrose
Journal:  Med Clin North Am       Date:  2000-11       Impact factor: 5.456

6.  Graded challenge in an aciclovir allergic patient.

Authors:  M Kawsar; J M Parkin; G Forster
Journal:  Sex Transm Infect       Date:  2001-06       Impact factor: 3.519

Review 7.  Comparative safety of tetracycline, minocycline, and doxycycline.

Authors:  L E Shapiro; S R Knowles; N H Shear
Journal:  Arch Dermatol       Date:  1997-10

Review 8.  Allergic reactions to drugs and biologic agents.

Authors:  R D deShazo; S F Kemp
Journal:  JAMA       Date:  1997-12-10       Impact factor: 56.272

9.  Vancomycin hypersensitivity: synergism with narcotics and "desensitization" by a rapid continuous intravenous protocol.

Authors:  J T Wong; R E Ripple; J A MacLean; D R Marks; K J Bloch
Journal:  J Allergy Clin Immunol       Date:  1994-08       Impact factor: 10.793

10.  Evidence of antibodies to erythromycin in serum of a patient following an episode of acute drug-induced hepatitis.

Authors:  M J Gómez-Lechón; J Carrasquer; J Berenguer; J V Castell
Journal:  Clin Exp Allergy       Date:  1996-05       Impact factor: 5.018

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  3 in total

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Journal:  Curr Allergy Asthma Rep       Date:  2008-03       Impact factor: 4.806

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Review 3.  Bioprocess engineering issues that would be faced in producing a DNA vaccine at up to 100 m3 fermentation scale for an influenza pandemic.

Authors:  Mike Hoare; M Susana Levy; Daniel G Bracewell; Steven D Doig; Simyee Kong; Nigel Titchener-Hooker; John M Ward; Peter Dunnill
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