Literature DB >> 6980179

Suppression of T lymphocyte proliferation during lymphoma growth in mice: role of PGE2-producing suppressor macrophages.

D Gemsa, H G Leser, W Deimann, K Resch.   

Abstract

The suppressed T lymphocyte response occurring during lymphoma growth in mice was largely due to the generation of suppressor macrophages which released high amounts of prostaglandin E2 (PGE2). Based on these findings, the role of macrophage-derived PGE2 as a regulating and potentially immunosuppressive agent of the immune response is discussed.

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Year:  1982        PMID: 6980179     DOI: 10.1016/s0171-2985(82)80096-x

Source DB:  PubMed          Journal:  Immunobiology        ISSN: 0171-2985            Impact factor:   3.144


  10 in total

1.  Activation of macrophages in an experimental rat model of arthritis induced by Erysipelothrix rhusiopathiae infection.

Authors:  H Renz; U Gentz; A Schmidt; T Dapper; M Nain; D Gemsa
Journal:  Infect Immun       Date:  1989-10       Impact factor: 3.441

Review 2.  Exercise and the immune response.

Authors:  D Keast; K Cameron; A R Morton
Journal:  Sports Med       Date:  1988-04       Impact factor: 11.136

3.  On the angiostructure of lymph nodes in Hodgkin's disease. An immunohistochemical study using the lectin I of Ulex europaeus as endothelial marker.

Authors:  P Möller; K Lennert
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1984

4.  Opioid-mediated suppression of interferon-gamma production by cultured peripheral blood mononuclear cells.

Authors:  P K Peterson; B Sharp; G Gekker; C Brummitt; W F Keane
Journal:  J Clin Invest       Date:  1987-09       Impact factor: 14.808

5.  Alternatively activated macrophages actively inhibit proliferation of peripheral blood lymphocytes and CD4+ T cells in vitro.

Authors:  C Schebesch; V Kodelja; C Müller; N Hakij; S Bisson; C E Orfanos; S Goerdt
Journal:  Immunology       Date:  1997-12       Impact factor: 7.397

Review 6.  Exercise and the immune system. Natural killer cells, interleukins and related responses.

Authors:  R J Shephard; S Rhind; P N Shek
Journal:  Sports Med       Date:  1994-11       Impact factor: 11.136

7.  The effect of indomethacin on the activation and effector function of suppressor cells from tumor-bearing mice.

Authors:  B L Pope
Journal:  Cancer Immunol Immunother       Date:  1985       Impact factor: 6.968

8.  Immunosuppression in murine renal cell carcinoma. II. Identification of responsible lymphoid cell phenotypes and examination of elimination of suppression.

Authors:  S K Gregorian; J R Battisto
Journal:  Cancer Immunol Immunother       Date:  1990       Impact factor: 6.968

Review 9.  Prostaglandin E2 and T cells: friends or foes?

Authors:  Vinatha Sreeramkumar; Manuel Fresno; Natalia Cuesta
Journal:  Immunol Cell Biol       Date:  2011-09-27       Impact factor: 5.126

Review 10.  Cyclo-Oxygenase (COX) Inhibitors and Cardiovascular Risk: Are Non-Steroidal Anti-Inflammatory Drugs Really Anti-Inflammatory?

Authors:  Shanzana Khan; Karen L Andrews; Jaye P F Chin-Dusting
Journal:  Int J Mol Sci       Date:  2019-08-30       Impact factor: 5.923

  10 in total

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