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Literature DB >> 6969207

alpha 1-Antitrypsin-levels and phenotypes in Crohn's disease in the Netherlands.

Abstract

A group of 310 unrelated patients suffering from Crohn's disease has been screened for quantitative and electrophoretic variations of alpha 1-antitrypsin (alpha 1AT). A comparison was made betweeen patients and healthy controls. The distribution of electrophoretic alpha 1AT variants in the patients showed no significant deviation from the controls. The alpha 1AT quantities are significantly higher in the Crohn's disease population than in the controls.

Entities: Disease Gene Species

Mesh：

Substances：
alpha 1-Antitrypsin

Year: 1980 PMID： 6969207 PMCID： PMC1419377 DOI： 10.1136/gut.21.10.840

Source DB: PubMed Journal: Gut ISSN： 0017-5749 Impact factor: 23.059

15 in total

1. Data on the genetic linkage relationships between red cell acid phosphatase and alpha1-antitrypsin variants Z, S, I, and F.

Authors: L R Weitkamp; D W Cox; E Johnston; S A Guttormsen; R H Schwartz; W B Bias; S H Hsu
Journal: Cytogenet Cell Genet Date: 1976

3. Diminished neutrophil function in Crohn's disease and ulcerative colitis identified by decreased oxidative metabolism and low superoxide dismutase content.

Authors: H W Verspaget; A S Peña; I T Weterman; C B Lamers
Journal: Gut Date: 1988-02 Impact factor: 23.059

3 in total

alpha 1-Antitrypsin-levels and phenotypes in Crohn's disease in the Netherlands.

1. Data on the genetic linkage relationships between red cell acid phosphatase and alpha1-antitrypsin variants Z, S, I, and F.

2. Alpha-1-antitrypsin, autism, and coeliac disease.

3. Cirrhosis associated with alpha-1-antitrypsin deficiency: a previously unrecognized inherited disorder.

4. Immunochemical quantitation of antigens by single radial immunodiffusion.

5. Quantitative studies on the inherited variants of serum alpha-1-antitrypsin.

6. Serum prealbumin: polymorphism in man.

7. Population genetics of alpha1-antitrypsin in the Netherlands. Description of a new electrophoretic variant.

8. Improved estimate of the Gm-Pi linkage.

9. alpha 1-antitrypsin phenotypes in rheumatoid arthritis and ankylosing spondylitis.

10. Rheumatoid arthritis and alpha-1-antitrypsin.

1. Predictors of acute relapse of Crohn's disease. A laboratory and clinical study.

Review 2. Macrophage activation, chronic inflammation and gastrointestinal disease.

3. Diminished neutrophil function in Crohn's disease and ulcerative colitis identified by decreased oxidative metabolism and low superoxide dismutase content.