Literature DB >> 6965708

Effects of acute lithium administration on conditioned avoidance behavior and monoamine synthesis in rats.

U Berggren, S Ahlenius, J Engel.   

Abstract

The effect of a single injection of various doses of lithium chloride was tested on conditioned avoidance behavior and on the accumulation of DOPA and 5-HTP after inhibition of aromatic amino acid decarboxylase. Lithium specifically suppressed conditioned avoidance behavior and reduced formation of DOPA, but not 5-HTP. The behavioral effect of lithium could be completely antagonized with additional L-DOPA treatment. The results indicate that lithium has a neuroleptlike effect on avoidance behavior, and it is suggested that some of the behavioral effects of lithium may be mediated via interference with central catecholaminergic mechanisms.

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Year:  1980        PMID： 6965708     DOI： 10.1007/BF01256634

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  18 in total

1.  Effect of lithium and other drugs on the amphetamine chlordiazeposice hyperactivity in mice.

Authors:  P Poitou; R Boulu; C Bohuon
Journal:  Experientia       Date:  1975-01-15

2.  A fluorometric method for the estimation of tyrosine in plasma and tissues.

Authors:  T P WAALKES; S UDENFRIEND
Journal:  J Lab Clin Med       Date:  1957-11

3.  Antagonism by locally applied dopamine into the nucleus accumbens or the corpus striatum of alpha-methyltyrosine-induced disruption of conditioned avoidance behaviour.

Authors:  D M Jackson; S Ahlenius; N E Andén; J Engel
Journal:  J Neural Transm       Date:  1977       Impact factor: 3.575

4.  Effect of chronic lithium treatment on monoamine metabolism in rat brain.

Authors:  J Schubert
Journal:  Psychopharmacologia       Date:  1973-09-28

5.  An improved method for the fluorimetric determination of 5-hydroxytryptamine in tissues.

Authors:  N E Andén; T Magnusson
Journal:  Acta Physiol Scand       Date:  1967 Jan-Feb

6.  Quantitative estimation of 5-hydroxy-3-indole acetic acid and 5-hydroxytryptophan in the brain following isolation by means of a strong cation exchange column.

Authors:  M Lindqvist
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1971

7.  Neuronally activated metabolism of brain serotonin: effect of lithium.

Authors:  M H Sheard; G K Aghajanian
Journal:  Life Sci       Date:  1970-03-01       Impact factor: 5.037

8.  Behavioral and biochemical effects of L-dopa after peripheral decarboxylase inhibition.

Authors:  L L Butcher; J Engel
Journal:  Brain Res       Date:  1969-09       Impact factor: 3.252

9.  The effect of lithium on amphetamine-induced locomotor stimulation.

Authors:  U Berggren; L Tallstedt; S Ahlenius; J Engel
Journal:  Psychopharmacology (Berl)       Date:  1978-09-15       Impact factor: 4.530

10.  A method for the determination of 3,4-dihydroxyphenylalanine (DOPA) in brain.

Authors:  W Kehr; A Carlsson; M Lindqvist
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1972       Impact factor: 3.000
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  5 in total

1.  The effect of lithium on the locomotor stimulation induced by dependence-producing drugs.

Authors:  U Berggren; J Engel; S Liljequist
Journal:  J Neural Transm       Date:  1981       Impact factor: 3.575

2.  Effects of chronic lithium treatment on brain monoamine metabolism and amphetamine-induced locomotor stimulation in rats.

Authors:  U Berggren
Journal:  J Neural Transm       Date:  1985       Impact factor: 3.575

3.  Acute lithium administration selectively lowers tyrosine levels in serum and brain.

Authors:  Hewlet G McFarlane; John Steele; Keenan Vinion; Rodolfo Bongiovanni; Manda Double; George E Jaskiw
Journal:  Brain Res       Date:  2011-08-27       Impact factor: 3.252

4.  The effect of acute lithium administration on brain monoamine synthesis and the precursor amino acids tyrosine and tryptophan in brain and plasma in rats.

Authors:  U Berggren
Journal:  J Neural Transm       Date:  1985       Impact factor: 3.575

Review 5.  Neuromolecular Etiology of Bipolar Disorder: Possible Therapeutic Targets of Mood Stabilizers.

Authors:  Jung Goo Lee; Young Sup Woo; Sung Woo Park; Dae-Hyun Seog; Mi Kyoung Seo; Won-Myong Bahk
Journal:  Clin Psychopharmacol Neurosci       Date:  2022-05-31       Impact factor: 3.731
  5 in total

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