Literature DB >> 4086991

Effects of chronic lithium treatment on brain monoamine metabolism and amphetamine-induced locomotor stimulation in rats.

U Berggren.   

Abstract

The aim of the present study was to investigate how chronic lithium treatment affects brain monoamine metabolism and amphetamine-induced locomotor stimulation in rats. Chronic lithium treatment was found to increase the synthesis of brain 5-hydroxytryptamine, an effect which may be mediated via increased brain levels of tryptophan. The synthesis and release of dopamine were, on the other hand, found to be decreased. Finally, chronic lithium treatment was found to suppress amphetamine-induced locomotor stimulation, probably due to counteraction by lithium on amphetamine-induced release of catecholamines.

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Year:  1985        PMID: 4086991     DOI: 10.1007/BF01256470

Source DB:  PubMed          Journal:  J Neural Transm            Impact factor:   3.575


  25 in total

1.  Does dopamine play a role in schizophrenia?

Authors:  A Carlsson
Journal:  Psychol Med       Date:  1977-11       Impact factor: 7.723

2.  Effect of lithium on brain dopamine.

Authors:  E Friedman; S Gershon
Journal:  Nature       Date:  1973-06-29       Impact factor: 49.962

3.  Effect of lithium on central metabolism of 5-hydroxytryptamine.

Authors:  P Poitou; F Guerinot; C Bohuon
Journal:  Psychopharmacologia       Date:  1974

4.  Neuronally activated metabolism of brain serotonin: effect of lithium.

Authors:  M H Sheard; G K Aghajanian
Journal:  Life Sci       Date:  1970-03-01       Impact factor: 5.037

Review 5.  Undernutrition and the development of brain neurotransmitter systems.

Authors:  R C Wiggins; G Fuller; S J Enna
Journal:  Life Sci       Date:  1984-11-19       Impact factor: 5.037

6.  The effect of lithium on the locomotor stimulation induced by dependence-producing drugs.

Authors:  U Berggren; J Engel; S Liljequist
Journal:  J Neural Transm       Date:  1981       Impact factor: 3.575

7.  Lithium enhancement of central 5-HT transmission induced by 5-HT precursors.

Authors:  C Sangdee; D N Franz
Journal:  Biol Psychiatry       Date:  1980-02       Impact factor: 13.382

Review 8.  The contribution of drug research to investigating the nature of endogenous depression.

Authors:  A Carlsson
Journal:  Pharmakopsychiatr Neuropsychopharmakol       Date:  1976-01

9.  Long-term treatment with lithium prevents the development of dopamine receptor supersensitivity.

Authors:  A Pert; J E Rosenblatt; C Sivit; C B Pert; W E Bunney
Journal:  Science       Date:  1978-07-14       Impact factor: 47.728

10.  Lithium inhibition of norepinephrine and dopamine receptors.

Authors:  A Flemenbaum
Journal:  Biol Psychiatry       Date:  1977-08       Impact factor: 13.382

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  10 in total

1.  Adaptive changes in the rat dopaminergic transmission following repeated lithium administration.

Authors:  M Dziedzicka-Wasylewska; M Maćkowiak; K Fijat; K Wedzony
Journal:  J Neural Transm (Vienna)       Date:  1996       Impact factor: 3.575

2.  The effect of chronic lithium administration and withdrawal on locomotor activity and apomorphine-induced locomotor stimulation in rats.

Authors:  U Berggren
Journal:  J Neural Transm       Date:  1988       Impact factor: 3.575

Review 3.  Lithium and serotonin function: implications for the serotonin hypothesis of depression.

Authors:  L H Price; D S Charney; P L Delgado; G R Heninger
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

4.  Modeling bipolar disorder in mice by increasing acetylcholine or dopamine: chronic lithium treats most, but not all features.

Authors:  Jordy van Enkhuizen; Morgane Milienne-Petiot; Mark A Geyer; Jared W Young
Journal:  Psychopharmacology (Berl)       Date:  2015-07-05       Impact factor: 4.530

5.  Chronic lithium treatment and status epilepticus induced by lithium and pilocarpine cause selective changes of amino acid concentrations in rat brain regions.

Authors:  R S Jope; J M Miller; T N Ferraro; T A Hare
Journal:  Neurochem Res       Date:  1989-09       Impact factor: 3.996

6.  Effects of acute and chronic lithium treatment on amphetamine-induced dopamine increase in the nucleus accumbens and prefrontal cortex in rats as studied by microdialysis.

Authors:  T Baptista; L Teneúd; Q Contreras; J L Burguera; M Burguera; L Hernández
Journal:  J Neural Transm Gen Sect       Date:  1993

7.  The additive effects of quinine on antidepressant drugs in the forced swimming test in mice.

Authors:  W Y Guo; K G Todd; M Bourin; M Hascoet
Journal:  Psychopharmacology (Berl)       Date:  1995-09       Impact factor: 4.530

8.  Effects of short-term lithium administration on tryptophan levels and 5-hydroxytryptamine synthesis in whole brain and brain regions in rats.

Authors:  U Berggren
Journal:  J Neural Transm       Date:  1987       Impact factor: 3.575

Review 9.  The behavioral actions of lithium in rodent models: leads to develop novel therapeutics.

Authors:  Kelley C O'Donnell; Todd D Gould
Journal:  Neurosci Biobehav Rev       Date:  2007-04-13       Impact factor: 8.989

10.  Chronic treatment with mood-stabilizers attenuates abnormal hyperlocomotion of GluA1-subunit deficient mice.

Authors:  Milica Maksimovic; Olga Y Vekovischeva; Teemu Aitta-aho; Esa R Korpi
Journal:  PLoS One       Date:  2014-06-16       Impact factor: 3.240

  10 in total

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