Literature DB >> 6960114

Enhancement of the 7 alpha-dehydroxylase activity of a gram-positive intestinal anaerobe by Bacteroides and its significance in the 7-dehydroxylation of ursodeoxycholic acid.

S Hirano, N Masuda.   

Abstract

The 7 alpha-dehydroxylation of chenodeoxycholic acid (CDCA) and cholic acid (CA) by a Eubacterium lentum-like intestinal anaerobe was specifically enhanced by the bacteroides present in mixed cultures and also by the addition to the growth medium of cell extracts from the bacteroides. The 7 alpha-dehydroxylating organism also possessed 7 alpha-hydroxysteroid dehydrogenase activity, and, in collaboration with a 7 beta-dehydrogenating organism, converted ursodeoxycholic acid (UDCA) into CDCA. Large quantities of lithocholic acids were produced from UDCA as well as CDCA in in vitro cocultures of these three kinds of microorganisms.

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Year:  1982        PMID： 6960114

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


  16 in total

Review 1.  The gut microbiota modulates both browning of white adipose tissue and the activity of brown adipose tissue.

Authors:  José María Moreno-Navarrete; José Manuel Fernandez-Real
Journal:  Rev Endocr Metab Disord       Date:  2019-12       Impact factor: 6.514

2.  The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids.

Authors:  Puneet Puri; Kalyani Daita; Andrew Joyce; Faridoddin Mirshahi; Prasanna K Santhekadur; Sophie Cazanave; Velimir A Luketic; Mohammad S Siddiqui; Sherry Boyett; Hae-Ki Min; Divya P Kumar; Rohit Kohli; Huiping Zhou; Phillip B Hylemon; Melissa J Contos; Michael Idowu; Arun J Sanyal
Journal:  Hepatology       Date:  2017-12-23       Impact factor: 17.425

3.  Formation of hyodeoxycholic acid from muricholic acid and hyocholic acid by an unidentified gram-positive rod termed HDCA-1 isolated from rat intestinal microflora.

Authors:  H J Eyssen; G De Pauw; J Van Eldere
Journal:  Appl Environ Microbiol       Date:  1999-07       Impact factor: 4.792

4.  Transformation of bile acids and sterols by clostridia (fusiform bacteria) in Wistar rats.

Authors:  K Uchida; T Satoh; S Narushima; K Itoh; H Takase; K Kuruma; H Nakao; N Yamaga; K Yamada
Journal:  Lipids       Date:  1999-03       Impact factor: 1.880

5.  Helicobacter hepaticus--induced liver tumor promotion is associated with increased serum bile acid and a persistent microbial-induced immune response.

Authors:  Alexis García; Yu Zeng; Sureshkumar Muthupalani; Zhongming Ge; Amanda Potter; Melissa W Mobley; Chakib Boussahmain; Yan Feng; John S Wishnok; James G Fox
Journal:  Cancer Res       Date:  2011-02-18       Impact factor: 12.701

6.  Ursodeoxycholic Acid and Its Taurine- or Glycine-Conjugated Species Reduce Colitogenic Dysbiosis and Equally Suppress Experimental Colitis in Mice.

Authors:  Lien Van den Bossche; Pieter Hindryckx; Lindsey Devisscher; Sarah Devriese; Sophie Van Welden; Tom Holvoet; Ramiro Vilchez-Vargas; Marius Vital; Dietmar H Pieper; Julie Vanden Bussche; Lynn Vanhaecke; Tom Van de Wiele; Martine De Vos; Debby Laukens
Journal:  Appl Environ Microbiol       Date:  2017-03-17       Impact factor: 4.792

7.  7 alpha-Dehydroxylation of bile acids by resting cells of a Eubacterium lentum-like intestinal anaerobe, strain c-25.

Authors:  N Masuda; H Oda; S Hirano; M Masuda; H Tanaka
Journal:  Appl Environ Microbiol       Date:  1984-04       Impact factor: 4.792

8.  Intestine farnesoid X receptor agonist and the gut microbiota activate G-protein bile acid receptor-1 signaling to improve metabolism.

Authors:  Preeti Pathak; Cen Xie; Robert G Nichols; Jessica M Ferrell; Shannon Boehme; Kristopher W Krausz; Andrew D Patterson; Frank J Gonzalez; John Y L Chiang
Journal:  Hepatology       Date:  2018-05-21       Impact factor: 17.425

Review 9.  Latest development in the synthesis of ursodeoxycholic acid (UDCA): a critical review.

Authors:  Fabio Tonin; Isabel W C E Arends
Journal:  Beilstein J Org Chem       Date:  2018-02-20       Impact factor: 2.883

10.  Decreased ω-6:ω-3 PUFA ratio attenuates ethanol-induced alterations in intestinal homeostasis, microbiota, and liver injury.

Authors:  Dennis R Warner; Jeffrey B Warner; Josiah E Hardesty; Ying L Song; Taylor N King; Jing X Kang; Chih-Yu Chen; Shanfu Xie; Fang Yuan; Md Aminul Islam Prodhan; Xipeng Ma; Xiang Zhang; Eric C Rouchka; Krishna Rao Maddipati; Joan Whitlock; Eric C Li; Gary P Wang; Craig J McClain; Irina A Kirpich
Journal:  J Lipid Res       Date:  2019-10-04       Impact factor: 5.922
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