| Literature DB >> 6950412 |
J H Sher, A Stracher, S A Shafiq, J Hardy-Stashin.
Abstract
Mice with genetic muscular dystrophy were treated with intraperitoneal injections of the proteinase inhibitor leupeptin, beginning before the onset of weakness. A significant number of the treated animals failed to develop histological evidence of dystrophy, compared with controls. Leupeptin treatment prevented (or delayed) the onset of muscular dystrophy in this experiment.Entities:
Mesh：
Substances：
Year: 1981 PMID： 6950412 PMCID： PMC349346 DOI： 10.1073/pnas.78.12.7742
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205