| Literature DB >> 635570 |
A Stracher, E B McGowan, S A Shafiq.
Abstract
The protease inhibitors leupeptin and pepstatin were used in vivo in genetically dystrophic chickens to determine their effects on the histological and biochemical changes observed in this disease. These compounds appear to delay the degeneration of muscle tissue which is characteristic of this disorder and thus may have potential therapeutic value in the treatment of muscular dystrophy.Entities:
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Year: 1978 PMID： 635570 DOI： 10.1126/science.635570
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728