| Literature DB >> 6950346 |
R Rossmeisl, A Reader, R Melfi, J Marquard.
Abstract
Thirty-two fully formed vital teeth of four adult cynomolgus monkeys were endodontically prepared to simulate conditions of an open apex. The apical 2 to 5 mm. of 24 teeth were filled with freeze-dried dentin. The eight remaining teeth received no implant material and served as controls. All the teeth were obturated with gutta-percha. The monkeys were sacrificed at 6, 13, 23, and 27 week periods, and the specimens were prepared for histologic examination. The early specimens showed acute inflammation apically; later specimens showed osseous healing. Some experimental teeth had partial cementum bridging against the implant material. Freeze-dried dentin was found to be a biocompatible material which can be used effectively as a substitute barrier against which gutta-percha can be condensed in mechanically prepared open-apexed monkey teeth.Entities:
Mesh：
Substances：
Year: 1982 PMID： 6950346 DOI： 10.1016/0030-4220(82)90307-3
Source DB: PubMed Journal: Oral Surg Oral Med Oral Pathol ISSN： 0030-4220