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Literature DB >> 6947718

Transformation of bile acids by Eubacterium lentum.

Abstract

A group of fecal isolates identified as Eubacterium lentum elaborated 3 alpha-, 7 alpha-, and 12 alpha-dehydrogenases and also an epimerizing enzyme(s) for the 3 alpha-hydroxy group. The activities of the enzymes, however, were variably manifested according to the kind of bile acid substrate and the oxygen tension under which the reaction occurred.

Entities: Chemical Species

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Year: 1981 PMID： 6947718 PMCID： PMC244126 DOI： 10.1128/aem.42.5.912-915.1981

Source DB: PubMed Journal: Appl Environ Microbiol ISSN： 0099-2240 Impact factor: 4.792

10 in total

1. NAD-dependent 3alpha- and 12alpha-hydroxysteroid dehydrogenase activities from Eubacterium lentum ATCC no. 25559.

Authors: I A MacDonald; D E Mahony; J F Jellet; C E Meier
Journal: Biochim Biophys Acta Date: 1977-12-21

2. Identification of 7alpha-, 12alpha-dihydroxy-3-oxo cholanoic acid as the major degradation product from cholic by C. perfringens.

Authors: I A Macdonald; T P Forrest; G A Costain; B G Rao
Journal: J Steroid Biochem Date: 1978-04 Impact factor: 4.292

3. Partial purification and characterization of NADP-dependent 12alpha-hydroxysteroid dehydrogenase from Clostridium leptum.

Authors: J N Harris; P B Hylemon
Journal: Biochim Biophys Acta Date: 1978-01-27

4. Isolation and characterization of human fecal bacteria capable of 21-dehydroxylating corticoids.

Authors: V D Bokkenheuser; J Winter; P Dehazya; W G Kelly
Journal: Appl Environ Microbiol Date: 1977-11 Impact factor: 4.792

5. Degradation of steroids by intestinal bacteria. II. Enzymes catalysing the oxidoreduction of the 3 alpha-, 7 alpha- and 12 alpha-hydroxyl groups in cholic acid, and the dehydroxylation of the 7-hydroxyl group.

Authors: V Aries; M J Hill
Journal: Biochim Biophys Acta Date: 1970-05-05

6. Bile acid transformations by microbial strains belonging to genera found in intestinal contents.

Authors: T Midtvedt; A Norman
Journal: Acta Pathol Microbiol Scand Date: 1967

7. Bile salt 3 alpha- and 12 alpha-hydroxysteroid dehydrogenases from Eubacterium lentum and related organisms.

Authors: I A MacDonald; J F Jellett; D E Mahony; L V Holdeman
Journal: Appl Environ Microbiol Date: 1979-05 Impact factor: 4.792

8. Transformation of bile acids by mixed microbial cultures from human feces and bile acid transforming activities of isolated bacterial strains.

Authors: S Hirano; N Masuda; H Oda; T Imamura
Journal: Microbiol Immunol Date: 1981 Impact factor: 1.955

9. Transformation of bile acids by Clostridium perfringens.

Authors: S Hirano; N Masuda; H Oda; H Mukai
Journal: Appl Environ Microbiol Date: 1981-09 Impact factor: 4.792

10. Isolation and characterization of thirteen intestinal microorganisms capable of 7 alpha-dehydroxylating bile acids.

Authors: S Hirano; R Nakama; M Tamaki; N Masuda; H Oda
Journal: Appl Environ Microbiol Date: 1981-03 Impact factor: 4.792

10 in total

17 in total

1. Biogeography of microbial bile acid transformations along the murine gut.

Authors: Solenne Marion; Lyne Desharnais; Nicolas Studer; Yuan Dong; Matheus D Notter; Suresh Poudel; Laure Menin; Andrew Janowczyk; Robert L Hettich; Siegfried Hapfelmeier; Rizlan Bernier-Latmani
Journal: J Lipid Res Date: 2020-07-13 Impact factor: 5.922

2. A study on the mechanism of the epimerization at C-3 of chenodeoxycholic acid by Clostridium perfringens.

Authors: F Aragozzini; E Canzi; A Ferrari; E Maconi; A Sidjimov
Journal: Biochem J Date: 1985-09-01 Impact factor: 3.857

3. Metabolism of Oxo-Bile Acids and Characterization of Recombinant 12α-Hydroxysteroid Dehydrogenases from Bile Acid 7α-Dehydroxylating Human Gut Bacteria.

Authors: Heidi Doden; Lina A Sallam; Saravanan Devendran; Lindsey Ly; Greta Doden; Steven L Daniel; João M P Alves; Jason M Ridlon
Journal: Appl Environ Microbiol Date: 2018-05-01 Impact factor: 4.792

4. Biotransformation of linoleic acid and bile acids by Eubacterium lentum.

Authors: H Eyssen; A Verhulst
Journal: Appl Environ Microbiol Date: 1984-01 Impact factor: 4.792

5. Characterization and regulation of the NADP-linked 7 alpha-hydroxysteroid dehydrogenase gene from Clostridium sordellii.

Authors: J P Coleman; L L Hudson; M J Adams
Journal: J Bacteriol Date: 1994-08 Impact factor: 3.490

6. Partial purification and characterization of an NAD-dependent 3 beta-hydroxysteroid dehydrogenase from Clostridium innocuum.

Authors: R Edenharder; M Pfützner
Journal: Appl Environ Microbiol Date: 1989-06 Impact factor: 4.792