Literature DB >> 6941273

Translation of phenylalanine hydroxylase-specific mRNA in vitro: evidence for pretranslational control by glucocorticoids.

F Chiappelli, D F Haggerty, M Lynch, G Popják.   

Abstract

We have found that the induction of phenylalanine hydroxylase by hydrocortisone and serum in confluent cultures of H4-II-E-C3 rat hepatoma cells is accompanied by an increase in polysomal mRNA specific for phenylalanine hydroxylase, as measured by translation in a cell-free protein-synthesizing system. Thus, the induction is mediated largely, if not entirely, by a pretranslational mechanism, possibly by stimulation of the transcription of the phenylalanine hydroxylase gene.

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Year:  1981        PMID： 6941273      PMCID： PMC319292          DOI： 10.1073/pnas.78.4.2105

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  25 in total

1.  Effect of serum on phenylalanine hydroxylase levels in cultured hepatoma cells.

Authors:  D F Haggerty; P L Young; J V Buese; G Popják
Journal:  J Biol Chem       Date:  1975-11-10       Impact factor: 5.157

2.  Changes in RNA metabolism and accumulation of presumptive messenger RNA during transition from the growing to the quiescent state of cultured mouse fibroblasts.

Authors:  P S Rudland; S Weil; A R Hunter
Journal:  J Mol Biol       Date:  1975-08-25       Impact factor: 5.469

3.  Phenylalanine hydroxylase in cultured hepatoxytes. I. Hormonal control of enzyme levels.

Authors:  D F Haggerty; P L Young; G Popják; W H Carnes
Journal:  J Biol Chem       Date:  1973-01-10       Impact factor: 5.157

4.  A specific kinetic assay for phenylalanine hydroxylase.

Authors:  J Ayling; R Pirson; W Pirson; G Boehm
Journal:  Anal Biochem       Date:  1973-01       Impact factor: 3.365

5.  Analysis of bacteriophage T7 early RNAs and proteins on slab gels.

Authors:  F W Studier
Journal:  J Mol Biol       Date:  1973-09-15       Impact factor: 5.469

6.  Purification and some physical properties of phenylalanine hydroxylase from rat liver.

Authors:  S Kaufman; D B Fisher
Journal:  J Biol Chem       Date:  1970-09-25       Impact factor: 5.157

7.  Phenylalanine hydroxylase of Macaca irus A simple purification by affinity chromatography.

Authors:  R G Cotton; P J Grattan
Journal:  Eur J Biochem       Date:  1975-12-15

8.  Purification of rat liver phenylalanine hydroxylase by affinity chromatography.

Authors:  J M Al-Janabi
Journal:  Arch Biochem Biophys       Date:  1980-04-01       Impact factor: 4.013

9.  Characterization of a highly efficient protein synthesizing system derived from commercial wheat germ.

Authors:  K Marcu; B Dudock
Journal:  Nucleic Acids Res       Date:  1974-11       Impact factor: 16.971

10.  Steroid hormone regulation of specific messenger RNA and protein synthesis in eucaryotic cells.

Authors:  B W O'Malkey; S L Woo; S E Harris; J M Rosen; A R Means
Journal:  J Cell Physiol       Date:  1975-04       Impact factor: 6.384
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  6 in total

1.  The effect of streptozotocin-induced diabetes on phenylalanine hydroxylase expression in rat liver.

Authors:  D S Taylor; H H Dahl; J F Mercer; A K Green; M J Fisher
Journal:  Biochem J       Date:  1989-11-15       Impact factor: 3.857

2.  Regulation and crystallization of phosphorylated and dephosphorylated forms of truncated dimeric phenylalanine hydroxylase.

Authors:  B Kobe; I G Jennings; C M House; S C Feil; B J Michell; T Tiganis; M W Parker; R G Cotton; B E Kemp
Journal:  Protein Sci       Date:  1997-06       Impact factor: 6.725

Review 3.  Structure and function of the aromatic amino acid hydroxylases.

Authors:  S E Hufton; I G Jennings; R G Cotton
Journal:  Biochem J       Date:  1995-10-15       Impact factor: 3.857

4.  Development of the adrenergic phenotype: increase in adrenal messenger RNA coding for phenylethanolamine-N-methyltransferase.

Authors:  E Sabban; M Goldstein; M C Bohn; I B Black
Journal:  Proc Natl Acad Sci U S A       Date:  1982-08       Impact factor: 11.205

5.  The effect of experimental diabetes on phenylalanine metabolism in isolated liver cells.

Authors:  M A Santana; M J Fisher; A J Bate; C I Pogson
Journal:  Biochem J       Date:  1985-04-01       Impact factor: 3.857

6.  Salivary serotonin does not correlate with central serotonin turnover in adult phenylketonuria (PKU) patients.

Authors:  Joseph Leung; Caroline Selvage; Taryn Bosdet; Jennifer Branov; Annie Rosen-Heath; Carole Bishop; Sandra Sirrs; Gabriella Horvath
Journal:  Mol Genet Metab Rep       Date:  2018-04-05
  6 in total

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