| Literature DB >> 6935651 |
Abstract
The synthesis and evaluation of a new detergent that is a zwitterionic derivative of cholic acid is presented. This detergent combines the useful properties of both the sulfobetaine-type detergents and the bile salt anions. The new detergent proved to be effective at solubilizing membrane proteins in a nondenatured state.Entities:
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Year: 1980 PMID: 6935651 PMCID: PMC350285 DOI: 10.1073/pnas.77.11.6368
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205