Literature DB >> 6933516

Electron microscope study of duck globin mRNA precursor crosslinked in situ.

C Reymond, A Aglianó, G Spohr.   

Abstract

Double-stranded RNA segments present in duck globin pre-mRNA were crosslinked in situ with aminomethyltrioxalen and UV light. The secondary structure of the crosslinked pre-mRNA was then studied by electron-microscopic analysis of pre-mRNA . cDNA hybrids. The data suggest that duck globin pre-mRNAs contain intervening sequences that are excised stepwise. Excision and subsequent ligation appears to occur on precursor molecules that are stabilized by base-paired regions.

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Year:  1980        PMID： 6933516      PMCID： PMC349910          DOI： 10.1073/pnas.77.8.4683

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  22 in total

1.  Globin mRNA sequences in polyadenylated and nonpolyadenylated nuclear precursor-messenger RNA from avian erythroblasts.

Authors:  G Spohr; G Dettori; V Manzari
Journal:  Cell       Date:  1976-08       Impact factor: 41.582

2.  Intermolecular duplexes in heterogeneous nuclear RNA from HeLa cells.

Authors:  N Fedoroff; P K Wellauer; R Wall
Journal:  Cell       Date:  1977-04       Impact factor: 41.582

3.  Inverted repeated DNA from Chinese hamster ovary cells studied with cloned DNA fragments.

Authors:  W R Jelinek
Journal:  Proc Natl Acad Sci U S A       Date:  1978-06       Impact factor: 11.205

4.  Globin mRNA precursor. Cross-linking in situ of double-stranded segments with aminomethyltrioxalen.

Authors:  A M Aglianó; A Nacci; C Reymond; D Appleby; G Spohr
Journal:  Eur J Biochem       Date:  1979-03-15

5.  Secondary structure in heterogeneous nuclear RNA: involvement of regions from repeated DNA sites.

Authors:  W Jelinek; G Molloy; R Fernandez-Munoz; M Salditt; J E Darnell
Journal:  J Mol Biol       Date:  1974-01-25       Impact factor: 5.469

6.  A comparison of two cloned mouse beta-globin genes and their surrounding and intervening sequences.

Authors:  D C Tiemeier; S M Tilghman; F I Polsky; J G Seidman; A Leder; M H Edgell; P Leder
Journal:  Cell       Date:  1978-06       Impact factor: 41.582

7.  The precursor of mouse beta-globin messenger RNA contains two intervening RNA sequences.

Authors:  A J Kinniburgh; J E Mertz; J Ross
Journal:  Cell       Date:  1978-07       Impact factor: 41.582

8.  Are snRNPs involved in splicing?

Authors:  M R Lerner; J A Boyle; S M Mount; S L Wolin; J A Steitz
Journal:  Nature       Date:  1980-01-10       Impact factor: 49.962

9.  Determination of nucleotide sequences from double-stranded regions of HeLa cell nuclear RNA.

Authors:  H D Robertson; E Dickson; W Jelinek
Journal:  J Mol Biol       Date:  1977-10-05       Impact factor: 5.469

10.  Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA.

Authors:  S T Isaacs; C K Shen; J E Hearst; H Rapoport
Journal:  Biochemistry       Date:  1977-03-22       Impact factor: 3.162
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  3 in total

1.  Genetic test for involvement of intervening sequences in transport of nuclear RNA.

Authors:  L P Villarreal; S Carr
Journal:  Mol Cell Biol       Date:  1982-12       Impact factor: 4.272

2.  Characterization of two circular plasmids from the marine diatom Cylindrotheca fusiformis: plasmids hybridize to chloroplast and nuclear DNA.

Authors:  J D Jacobs; J R Ludwig; M Hildebrand; A Kukel; T Y Feng; R W Ord; B E Volcani
Journal:  Mol Gen Genet       Date:  1992-05

3.  Novel models for RNA splicing that involve a small nuclear RNA.

Authors:  Y Ohshima; M Itoh; N Okada; T Miyata
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205
  3 in total

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