Literature DB >> 275835

Inverted repeated DNA from Chinese hamster ovary cells studied with cloned DNA fragments.

W R Jelinek.   

Abstract

Fragments from the DNA of Chinese hamster ovary cells produced by restriction endonuclease EcoRI were cloned in Charon 16A lambda bacteriophage and examined for the ability to hybridize in situ with 32P-labeled double-stranded regions from heterogeneous nuclear RNA (hnRNA). Of 235 clones tested, 87 (37%) contained sequences that hybridized with the double-stranded hnRNA. Nine of these were examined for the presence of inverted repeat DNA structures (ir-DNA) by electron microscopy. All nine contained at least two elements of ir-DNA. Analysis of heteroduplexes formed from the DNAs of the different clones as well as T1 fingerprint analysis of the double-stranded hnRNA hybridized to each of the nine clones suggest that there is detectable nucleotide sequence homology in the various ir-DNAs. There are ca 3 X 10(5) ir-DNA pairs in the haploid Chinese hamster ovary cell genome.

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Year:  1978        PMID： 275835      PMCID： PMC392626          DOI： 10.1073/pnas.75.6.2679

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  15 in total

1.  Sequence organization of the human genome.

Authors:  C W Schmid; P L Deininger
Journal:  Cell       Date:  1975-11       Impact factor: 41.582

2.  An electron microscope study of the DNA sequence organization of the human genome.

Authors:  P L Deininger; C W Schmid
Journal:  J Mol Biol       Date:  1976-09-25       Impact factor: 5.469

3.  Screening lambdagt recombinant clones by hybridization to single plaques in situ.

Authors:  W D Benton; R W Davis
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

4.  Secondary structure in heterogeneous nuclear RNA: involvement of regions from repeated DNA sites.

Authors:  W Jelinek; G Molloy; R Fernandez-Munoz; M Salditt; J E Darnell
Journal:  J Mol Biol       Date:  1974-01-25       Impact factor: 5.469

5.  Double-stranded regions in heterogeneous nuclear RNA from Hela cells.

Authors:  W Jelinek; J E Darnell
Journal:  Proc Natl Acad Sci U S A       Date:  1972-09       Impact factor: 11.205

6.  General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopus.

Authors:  E H Davidson; B R Hough; C S Amenson; R J Britten
Journal:  J Mol Biol       Date:  1973-06-15       Impact factor: 5.469

7.  Charon phages: safer derivatives of bacteriophage lambda for DNA cloning.

Authors:  F R Blattner; B G Williams; A E Blechl; K Denniston-Thompson; H E Faber; L Furlong; D J Grunwald; D O Kiefer; D D Moore; J W Schumm; E L Sheldon; O Smithies
Journal:  Science       Date:  1977-04-08       Impact factor: 47.728

8.  Palindromes in chromosomes.

Authors:  D A Wilson; C A Thomas
Journal:  J Mol Biol       Date:  1974-03-25       Impact factor: 5.469

9.  Determination of nucleotide sequences from double-stranded regions of HeLa cell nuclear RNA.

Authors:  H D Robertson; E Dickson; W Jelinek
Journal:  J Mol Biol       Date:  1977-10-05       Impact factor: 5.469

10.  Inverted repeat sequences in the Drosophila genome.

Authors:  C W Schmid; J E Manning; N Davidson
Journal:  Cell       Date:  1975-06       Impact factor: 41.582
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  16 in total

1.  The Chinese hamster Alu-equivalent sequence: a conserved highly repetitious, interspersed deoxyribonucleic acid sequence in mammals has a structure suggestive of a transposable element.

Authors:  S R Haynes; T P Toomey; L Leinwand; W R Jelinek
Journal:  Mol Cell Biol       Date:  1981-07       Impact factor: 4.272

2.  Structure and evolution of a family of interspersed repetitive DNA sequences in Caenorhabditis elegans.

Authors:  K M Felsenstein; S W Emmons
Journal:  J Mol Evol       Date:  1987       Impact factor: 2.395

3.  Long double-stranded sequences (dsRNA-B) of nuclear pre-mRNA consist of a few highly abundant classes of sequences: evidence from DNA cloning experiments.

Authors:  D A Kramerov; A A Grigoryan; A P Ryskov; G P Georgiev
Journal:  Nucleic Acids Res       Date:  1979-02       Impact factor: 16.971

4.  Sequences hybridizing to mRNA, oligo(dT) and dsRNA from pre-mRNA are contiguous in the cloned mouse DNA fragments.

Authors:  O N Tokarskaya; N A Tchurikov; P L Ivanov; D A Kramerov; A P Ryskov
Journal:  Nucleic Acids Res       Date:  1980-02-11       Impact factor: 16.971

5.  Structure and distribution of Alu family sequences or their analogs within heterogeneous nuclear RNA of HeLa, KB, and L cells.

Authors:  H D Robertson; E Dickson
Journal:  Mol Cell Biol       Date:  1984-02       Impact factor: 4.272

6.  Small RNA molecules related to the Alu family of repetitive DNA sequences.

Authors:  L A Leinwand; R M Wydro; B Nadal-Ginard
Journal:  Mol Cell Biol       Date:  1982-11       Impact factor: 4.272

7.  Low molecular weight RNAs transcribed in vitro by RNA polymerase III from Alu-type dispersed repeats in Chinese hamster DNA are also found in vivo.

Authors:  S R Haynes; W R Jelinek
Journal:  Proc Natl Acad Sci U S A       Date:  1981-10       Impact factor: 11.205

8.  Structural variation among human beta-tubulin genes.

Authors:  N J Cowan; C D Wilde; L T Chow; F C Wefald
Journal:  Proc Natl Acad Sci U S A       Date:  1981-08       Impact factor: 11.205

9.  Electron microscope study of duck globin mRNA precursor crosslinked in situ.

Authors:  C Reymond; A Aglianó; G Spohr
Journal:  Proc Natl Acad Sci U S A       Date:  1980-08       Impact factor: 11.205

10.  Integration in vivo into simian virus 40 DNA of a sequence that resembles a certain family of genomic interspersed repeated sequences.

Authors:  B R Dhruva; T Shenk; K N Subramanian
Journal:  Proc Natl Acad Sci U S A       Date:  1980-08       Impact factor: 11.205
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