Literature DB >> 6933358

Serum theophylline levels in adult asthmatics: comparison of oral sustained-release and microcrystalline preparations.

D T Jones, M R Sears.   

Abstract

Serial serum theophylline levels were measured in 20 inpatient asthmatics given tablets of either microcrystalline or sustained-release theophylline. The sustained-release preparation gave serum levels which were more consistently within the therapeutic range with a significantly higher trough concentration. No increase in adverse effects was encountered.

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Year:  1980        PMID： 6933358

Source DB:  PubMed          Journal:  N Z Med J        ISSN： 0028-8446


  3 in total

Review 1.  A clinical and pharmacokinetic basis for the selection and use of slow release theophylline products.

Authors:  L Hendeles; R P Iafrate; M Weinberger
Journal:  Clin Pharmacokinet       Date:  1984 Mar-Apr       Impact factor: 6.447

2.  Disposition and clinical pharmacokinetics of theophylline after administration of a new sustained release tablet.

Authors:  J H Jonkman; W C Berg; K de Vries; R A de Zeeuw; R Schoenmaker; N Grimberg
Journal:  Eur J Clin Pharmacol       Date:  1981       Impact factor: 2.953

3.  Bioavailability and diurnal variation in absorption of sustained release theophylline in asthmatic children.

Authors:  K P Coulthard; D J Birkett; D R Lines; N Grgurinovich; J J Grygiel
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953
  3 in total

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